Grace Bio-Labs

Infobox_Company
company_name = Grace Bio-Labs
foundation = 1986
company_
company_slogan =
key_people = Charles McGrath
Jennipher Grudzien
Wendy Scholz
location = Bend, Oregon, USA
industry = Biotechnology, Research Products
products = Oncyte Nitrocellulose Film Slide Biochips
homepage = [http://www.gracebio.com www.gracebio.com]

Grace Bio-Labs is a global supplier of pharmaceutical, biomedical, and biochemical research products based in Bend, Oregon, United States. They are known as pioneers in the development of the thin-cast nitrocellulose biochip (aka: nitrocellulose slide, nitrocellulose film slide)Cytometrically coherent transfer of receptor proteins on microporous membrane. BioTechniques Vol. 11, No 3: 352-361, 1991.] ,High Definition cell analysis in situ using microporous films. Cell Vision, vol. 2, No 6: 499-590, 1995.] and the modern hybridization and incubation chambers for glass microscope slides.Mcgrath, Charles M.; Grudzien, Jennipher L.; Levine, Allan. Influence of Surface: Volume ratio of Reaction Chambers on Stoichiometry of Antibody-Based Reactions in Situ. Cell Vision, Vol 2, No. 2. 165-169, 1995.]

History

Originally based near Detroit, Michigan, and founded by Charles McGrath in 1986, Grace Bio Labs relocated to Bend, Oregon in May, 1990.Fact|date=July 2008

Products

With the aid of SBIR funding, Grace Bio-Labs was built on two main product types. The first is the incubation chamber for cell culture and analysis; the second is the Oncyte® nitrocellulose film slide. Their incubation and hybridization chambers are fluid delivery and containment products that increase sensitivity and efficiency in fluorescence and color-based protein and cell analyte assays. [http://www.biocompare.com/review/119/The-HybriWell-Sealing-System-from-Grace-Bio-Labs.html] Janitz, M. The HybriWell Sealing System from Grace Bio-Labs. BioCompare, January 1, 03. ] The Oncyte® nitrocellulose microporous film (nitrocellulose slide) is a biochip platform that captures and protects the 3-dimensional (tertiary) structure of biological material. Originally designed for tissue printingCytometrically coherent transfer of receptor proteins on microporous membrane. BioTechniques Vol. 11, No 3: 352-361, 1991.] and cell lysate capture, the film has flourished in proteomics. It is commonly used in automated and manual protein microarrays, and continues to increase throughput in proteomics research. [http://www.genengnews.com/articles/chtitem.aspx?tid=1242&chid=1 ] Assay: Protein Microarrays on Nitrocellulose Slides. Genetic Engineering and Biotechnology News, Vol. 26, No 2. Mary Ann Liebert, Inc. Publishers: Jan 15, 2006.]
Grace Bio-Labs also produces high-precision OEM and custom components for biomedical manufacturers; this constitutes a major share of their revenue.

Customer Base

Grace Bio-Labs sells to university research laboratories, biotech companies, private researchers and pharmaceutical companies. They mainly distribute to North America, Western and Central Europe, East Asia, and Southeast Asia.Fact|date=July 2008

References

External links

* [http://www.freepatentsonline.com/5192503.html Mcgrath, Charles; Grudzien, Jennipher. 1993. Probe Clip in Situ Assay Apparatus. U.S. Patent 5,192,503, filed May 23, 1990, and issued March 9, 1993.]
* [http://www.patentstorm.us/patents/5436152.html Soule, Herbert; Mcgrath, Charles. 1991. Immortal human mammary epithelial cell lines. U.S. Patent 5026637, filed February 28, 1989, and issued June, 25 1991.]
* [http://www.patentstorm.us/patents/7063979.html MacBeath, Gavin; Grudzien, Jennipher. 2006. Interface between substrates having microarrays and microtiter plates. US Patent 7063979, issued June 20, 2006.]