Genedata

Infobox Company
company_name = Genedata
company_logo =
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company_type = Private
genre =
foundation = 1997
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location = Basel, Switzerland
origins =
key_people = Othmar Pfannes CEO
area_served =
industry = Bioinformatics
products = See detailed listing
revenue =
operating_income =
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num_employees = 120+
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homepage = [http://www.genedata.com www.genedata.com]
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Genedata is a bioinformatics solution provider based in Basel, Switzerland. It provides products to the Pharmaceutical industry, Biotechnology, Agriculture and Academia worldwide. Genedata has received considerable positive attention in several independent industry publications such as GenomeWeb [http://www.genomeweb.com/cgi-bin/texis/scripts-genomeweb/genomeweb-search/search.html?query=genedata&Go.x=0&Go.y=0 GenomeWeb] ] , BioInform, and Bio-IT World [http://www.google.com/search?num=100&hl=en&newwindow=1&safe=off&q=site%3Abio-itworld.com+%22Genedata%22&btnG=Search Bio-IT World] ] .

As Member of the InnoMed PredTox research consortium Genedata is collaborating with major European pharma companies on the application of toxicogenomics in pharmaceutical development processes.

Products

* [http://www.genedata.com/products/phylosopher/index_eng.html/ Genedata Phylosopher] - Target-centric research information management
* [http://www.genedata.com/products/screener/ Genedata Screener] - Enterprise solution for High-throughput [Liming Chang Milbauer, Peng Wei, Judy Enenstein, Aixiang Jiang, Cheryl A. Hillery, J. Paul Scott, Stephen C. Nelson, Vidya Bodempudi, James N. Topper, Ruey-Bing Yang, Betsy Hirsch, Wei Pan, and Robert P. Hebbel, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate High-Throughput Screenings Genetic endothelial systems biology of sickle stroke risk", Blood. 2008; 111:3872-3879] [Zhijin Wu, Dongmei Liu, and Yunxia Sui, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate High-Throughput Screenings", J Biomol Screen. 2008; 13:159-167] and High-content Screening [Duerr et al. "Robust hit identification by quality assurance and multivariate data analysis of a high-content, cell-based assay", J Biomol Screen. 2007 Dec;12(8):1042-9 [http://jbx.sagepub.com/cgi/content/abstract/12/8/1042] ] data management and analysis
* [http://www.genedata.com/products/expressionist/index_eng.html/ Genedata Expressionist] - Biomarker discovery platform that integrates and analyzes gene expression [Nadine Zidek, Juergen Hellmann, Peter-Juergen Kramer, and Philip G. Hewitt, "Acute Hepatotoxicity: A Predictive Model Based on Focused Illumina Microarrays", Toxicol. Sci. 2007; 99(1): p. 289-302] [Walter Lucchesi, Gareth Brady, Oliver Dittrich-Breiholz, Michael Kracht, Rainer Russ, and Paul J. Farrell, "Differential gene regulation by Epstein-Barr virus Type 1 and Type 2 EBNA2",J Virol. 2008 May 14] [Ramiro Dip, Sarah Lenz, Jean-Philippe Antignac, Bruno Le Bizec, Hans Gmuender, and Hanspeter Naegeli, "Global gene expression profiles induced by phytoestrogens in human breast cancer cells",Endocr. Relat. Cancer. 2008; 15:161-173] [Andrea J. O'Hara, Wolfgang Vahrson, and Dirk P. Dittmer, "Gene alteration and precursor and mature microRNA transcription changes contribute to the miRNA signature of primary effusion lymphoma",Blood. 2008; 111:2347-2353] [Benita K.T. Tan, Lay Keng Tan, Kun Yu, Puay Hoon Tan, Ming Lee, Lang Hiong Sii, Chow Yin Wong, Gay Hui Ho, Allen W.Y. Yeo, Pierce K.H. Chow, Heng Nung Koong, Wei Sean Yong, Dennis T.H. Lim, London L.P.J. Ooi, Khee Chee Soo, and Patrick Tan, "Clinical Validation of a Customized Multiple Signature Microarray for Breast Cancer",Clin. Cancer Res. 2008; 14:461-469] [Suk Mei Wang, London Lucien P.J. Ooi, and Kam M. Hui, "Identification and Validation of a Novel Gene Signature Associated with the Recurrence of Human Hepatocellular Carcinoma", Clin. Cancer Res., Nov 2007; 13: 6275 - 6283] [Siew Leng Tai, Pascale Daran-Lapujade, Michael C. Walsh, Jack T. Pronk, and Jean-Marc Daran, "Acclimation of Saccharomyces cerevisiae to Low Temperature: A Chemostat-based Transcriptome Analysis", Mol. Biol. Cell, Oct 2007; 10.1091/mbc.E07-02-0131] [Carsten Lange, Diane Starrett, Julia Goetsch, Volker Gerke, and Ursula Rescher, "Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25", J. Leukoc. Biol. published 12 September 2007, 10.1189/jlb.0307158] [Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Jul 2007; 77: 165 - 171] [Kristin L.M. Boylan, Mary A. Gosse, Sarah E. Staggs, Siegfried Janz, Suzanne Grindle, Geoffrey S. Kansas, and Brian G. Van Ness, "A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma", Cancer Res., May 2007; 67: 4069 - 4078] [Kerstin Stemmer, Heidrun Ellinger-Ziegelbauer, Hans-Juergen Ahr, and Daniel R. Dietrich, "Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal Tumorigenesis", Cancer Res., May 2007; 67: 4052 - 4068] [Jeffrey D. Lande, Jagadish Patil, Na Li, Todd R. Berryman, Richard A. King, and Marshall I. Hertz, "Novel Insights into Lung Transplant Rejection by Microarray Analysis", Proceedings of the ATS, Jan 2007; 4: 44 - 51] [Thorsten Müller, Caoimhin G. Concannon, Manus W. Ward, Ciara M. Walsh, Anca L. Tirniceriu, Florian Tribl, Donat Kögel, Jochen H.M. Prehn, and Rupert Egensperger, "Modulation of Gene Expression and Cytoskeletal Dynamics by the Amyloid Precursor Protein Intracellular Domain (AICD)", Mol. Biol. Cell, Jan 2007; 18: 201 - 210] [Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Mar 2007; 10.1095/biolreprod.106.059493] [Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Müller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler, "The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF- B and Hypoxia-Inducible Factor-1alpha", J. Immunol., Mar 2007; 178: 3198 - 3207] , proteomics [Sebastian Wiese, Thomas Gronemeyer, Rob Ofman, Markus Kunze, Claudia P. Grou, Jose A. Almeida, Martin Eisenacher, Christian Stephan, Heiko Hayen, Lukas Schollenberger, Thomas Korosec, Hans R. Waterham, Wolfgang Schliebs, Ralf Erdmann, Johannes Berger, Helmut E. Meyer, Wilhelm Just, Jorge E. Azevedo, Ronald J. A. Wanders, and Bettina Warscheid, "Proteomic characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling", Mol. Cell. Proteomics. published 2 September 2007, 10.1074/mcp.M700169-MCP200] [Tetsuya Okano, Tadashi Kondo, Kiyonaga Fujii, Toshihide Nishimura, Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Yoshihiro Matsuno, Akihiko Gemma, Harbumi Kato, Shoji Kudoh, and Setsuo Hirohashi, "Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma", Mol. Cell. Clin. Cancer Res., Feb 2007; 13: 799 - 805] , metabolomics, as well as projects spanning across different technology domains ("cross-omics") like in toxicogenomics [Heidrun Ellinger-Ziegelbauer, Hans Gmuender, Arnd Brandenburg, Hans Juergen Ahr, "Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies", Mutation Research 637 2007 23-39]

External links

* [http://www.genedata.com Genedata Official Homepage]

ee also

* Bioinformatics companies
* toxicogenomics

References