TPCN1

TPCN1

protein
Name = two pore segment channel 1
caption =


width =
HGNCid = 18182
Symbol = TPCN1
AltSymbols =
EntrezGene = 53373
OMIM = 609666
RefSeq = NM_017901
UniProt = Q9ULQ1
PDB =
ECnumber =
Chromosome = 12
Arm = q
Band = 24.21
LocusSupplementaryData =

Two pore segment channel 1, also known as TPCN1 is a human gene. The protein encoded by this gene is an ion channel. In contrast to other calcium and sodium channels which have four homologous domains, each containing 6 transmembrane segments (S1 to S6), TPCN1 only contains two domain (each containing segments S1 to S6).cite journal | author = Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O | title = Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain | journal = DNA Res. | volume = 6 | issue = 5 | pages = 329–36 | year = 1999 | month = October | pmid = 10574461 | url = http://dnaresearch.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=10574461 | issn = ] cite journal | author = Ishibashi K, Suzuki M, Imai M | title = Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels | journal = Biochem. Biophys. Res. Commun. | volume = 270 | issue = 2 | pages = 370–6 | year = 2000 | month = April | pmid = 10753632 | doi = 10.1006/bbrc.2000.2435 | url = | issn = ] cite journal | author = Clapham DE, Garbers DL | title = International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 451–4 | year = 2005 | month = December | pmid = 16382101 | doi = 10.1124/pr.57.4.7 | url = | issn = ]

ee also

* Two-pore channel

References

External links

*


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Look at other dictionaries:

  • TPCN2 — protein Name = two pore segment channel 2 caption = width = HGNCid = 20820 Symbol = TPCN2 AltSymbols = EntrezGene = 219931 OMIM = RefSeq = NM 139075 UniProt = Q8NHX9 PDB = ECnumber = Chromosome = 11 Arm = q Band = 13.1 LocusSupplementaryData =… …   Wikipedia

  • Two-pore channel — protein Name = two pore segment channel 1 caption = width = HGNCid = 18182 Symbol = TPCN1 AltSymbols = EntrezGene = 53373 OMIM = 609666 RefSeq = NM 017901 UniProt = Q9ULQ1 PDB = ECnumber = Chromosome = 12 Arm = q Band = 24.21… …   Wikipedia

  • Ion channel family — Pfam box Symbol = Ion trans Name = Ion channel (eukariotic) width =250 caption =Potassium channel KvAP, structure in a membrane like environment. Calculated hydrocarbon boundaries of the lipid bilayer are indicated by red and blue dots. Pfam=… …   Wikipedia

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