Agonist-Antagonist

Agonist-Antagonist

In pharmacology the term agonist-antagonist is used to refer to a drug (usually, if not exclusively, psychoactive) which exhibits some properties of an agonist (a substance which fully activates the neuronal receptor that it attaches to) and some properties of an antagonist (a substance which attaches to a receptor but does not activate it or if it displaces an agonist at that receptor it seemingly deactivates it thereby reversing the effect of the agonist). The best known agonists and antagonists are opioids; morphine is an agonist to opioid receptors while naloxone (Narcan) is an antagonist.

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  • Agonist — For other meanings of agonist or agonism , see agonist (disambiguation). For a primary fictional character in a work, see Protagonist and Antagonist. Agonists …   Wikipedia

  • Antagonist — (griech. ανταγωνιστής, antagonistís, von αντι, anti, „gegen“ und άγω, ágo, „ich handle, bewege, führe“: „der Gegenhandelnde“, „der Gegenspieler“) bezeichnet: im allgemeinen einen Widersacher oder Gegner Antagonist (Literatur), der Gegenspieler… …   Deutsch Wikipedia

  • Agonist — (griechisch αγωνιστής agonistís ‚der Tätige‘, ‚Handelnde‘, ‚Führende‘) bezeichnet: Agonist (Anatomie), ein Muskel oder Teil des Nervensystems, der bei zunehmender Aktivität von seinem Gegenspieler mehr und mehr gehemmt wird Agonist… …   Deutsch Wikipedia

  • agonist — [ag′ə nist΄] n. [back form. < ANTAGONIST] 1. one who takes part in a struggle, as a main character in a drama 2. a muscle whose action on a joint or orifice is opposed by the action of another muscle, the antagonist …   English World dictionary

  • Agonist (muscle) — Agonist is a classification used to describe a muscle that causes specific movement or possibly several movements to occur through the process of its own contraction. This is typically a term designated for skeletal muscles. Agonists are also… …   Wikipedia

  • antagonist — antagònist m DEFINICIJA 1. onaj koji istupa protiv koga; s oprečnih pozicija; suparnik, protivnik, opr. agonist 2. fiziol. sustav, mišić ili organ koji djeluje suprotno drugome, opr. sinergist 3. (mn) farm. lijekovi suprotna djelovanja u odnosu… …   Hrvatski jezični portal

  • Agonist — A drug that binds to a receptor of a cell and triggers a response by the cell. An agonist often mimics the action of a naturally occurring substance. An agonist produces an action. It is the opposite of an antagonist which acts against and blocks …   Medical dictionary

  • Antagonist — In biochemistry, an antagonist acts against and blocks an action. For example, insulin lowers the level of glucose (sugar) in the blood, whereas another hormone called glucagon raises it; therefore, insulin and glucagon are antagonists. An… …   Medical dictionary

  • Antagonist (disambiguation) — An antagonist is a character opposing the protagonist in literature.Antagonist may also refer to: *Antagonist (muscle), a muscle type *Antagonist (medical) a drug that opposes the action of another drug *Antagonist (band), a New Zealand band… …   Wikipedia

  • Agonist (Pharmakologie) — Dosis Wirkungskurven von Agonisten, die zu einer vollen (voller Agonist) oder partiellen Aktivierung eines Rezeptors führen (Partialagonist). Als Agonist (griechisch αγωνιστής, agonistís der Tätige, Handelnde, Führende) wird in der Pharmakologie… …   Deutsch Wikipedia

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