- 2,3-Dichlorophenylpiperazine
-
2,3-Dichlorophenylpiperazine 
1-(2,3-dichlorophenyl)piperazineIdentifiers CAS number 41202-77-1 PubChem 851833 ChemSpider 744460 
Jmol-3D images Image 1 - Clc1c(Cl)c(ccc1)N2CCNCC2
- InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
Key: UDQMXYJSNNCRAS-UHFFFAOYSA-N
InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
Key: UDQMXYJSNNCRAS-UHFFFAOYAH
InChI=1/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
Key: UDQMXYJSNNCRAS-UHFFFAOYAH
Properties Molecular formula C10H12Cl2N2 Molar mass 231.12 g/mol Appearance brown oil Density 1.272g/cm3 °C Melting point 242-244°C
Boiling point 365.1°C @ 760mmHg
Hazards Flash point 174.6°C 
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references 2,3-Dichlorophenylpiperazine (2,3-DCPP) is a chemical compound. It is both a precursor in the synthesis of aripiprazole and one of its metabolites.[1][2] It is unknown whether 2,3-DCPP is pharmacologically active similarly to its close analogue 3-chlorophenylpiperazine (mCPP).
See also
- Aripiprazole
- mCPP
- pCPP
- Phenylpiperazine
References
- ^ Leś A, Badowska-Rosłonek K, Łaszcz M, Kamieńska-Duda A, Baran P, Kaczmarek Ł (2010). "Optimization of aripiprazole synthesis". Acta Poloniae Pharmaceutica 67 (2): 151–7. PMID 20369792.
- ^ Caccia S (August 2007). "N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed". Current Drug Metabolism 8 (6): 612–22. doi:10.2174/138920007781368908. PMID 17691920. http://www.bentham-direct.org/pages/content.php?CDM/2007/00000008/00000006/0005F.SGM.
Piperazines Simple piperazines
(no additional rings)1-Cyclohexylpiperazine • Aminoethylpiperazine • Diethylcarbamazine • HEPPS • Midafotel • Piperazine • PIPESPhenylpiperazines Acaprazine • Antrafenine • Aripiprazole • Batoprazine • Bifeprunox • BRL-15,572 • Ciprofloxacin • CSP-2503 • Dapiprazole • DCPP • DMPP • Diphenylpiperazine • Dropropizine • EGIS-12,233 • Elopiprazole • Eltoprazine • Enpiprazole • Ensaculin • Etoperidone • Flesinoxan • Flibanserin • Fluprazine • Itraconazole • Ketoconazole • Levodropropizine • Lorpiprazole • mCPP • Mefway • MeOPP • Mepiprazole • Naftopidil • Naphthylpiperazine • Nefazodone • Niaprazine • Oxypertine • Pardoprunox • pCPP • pFPP • Posaconazole • PRX-00023 • S-14,506 • S-14,671 • S-15,535 • SB-258,585 • SB-271,046 • SB-357,134 • SB-399,885 • Sonepiprazole • TFMPP • Tolpiprazole • Trazodone • Urapidil • Vesnarinone • Vilazodone • WAY-100,135 • WAY-100,635Benzylpiperazines 2C-B-BZP • Befuraline • Bifeprunox • Buclizine • BZP • Chlorbenzoxamine • DBZP • Fipexide • Imatinib • MBZP • MDBZP • Meclozine • Piberaline • Piribedil • Trimetazidine • VesnarinoneDiphenylalkylpiperazines
(benzhydrylalkylpiperazines)Almitrine • Amperozide • BRL-15,572 • Buclizine • BW373U86 • Cetirizine • Chlorbenzoxamine • Chlorcyclizine • Cinnarizine • Clocinizine • Cyclizine • DBL-583 • Diphenylmethylpiperazine • Dotarizine • DPI-221 • DPI-287 • DPI-3290 • GBR-12,783 • GBR-12,935 • GBR-13,069 • GBR-13,098 • GBR-13,119 • Hydroxyzine • Lidoflazine • Manidipine • Meclozine • Oxatomide • SNC-80 • VanoxerinePyrimidinylpiperazines Buspirone • Dasatinib • Eptapirone • Gepirone • Ipsapirone • Piribedil • Pyrimidinylpiperazine • Revospirone • Tandospirone • Tirilazad • Trimazosin • Umespirone • ZalospironePyridinylpiperazines Atevirdine • Azaperone • PyridinylpiperazineBenzo(iso)thiazolylpiperazines Tricyclics
(piperazine attached via side chain)Others 6-Nitroquipazine • Azimilide • Cinepazet • Cyclohexylpiperazine • Hexocyclium • Indinavir • JNJ-7777120 • Lodenafil • Mirodenafil • PB-28 • Quipazine • Ranolazine • SA-4503 • Sildenafil • Tadalafil • Vardenafil • VUF-6002 • Zipeprol
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