Lurasidone

Lurasidone

Drugbox
IUPAC_name = (3aR,4S,7R,7aS)-2- [(1R,2R)-2- [4-(1,2-Benzisothiazol-3-yl)-piperazin-1-ylmethyl] cyclohexylmethyl] hexahydro-1H-4,7-methanisoindol-1,3-dione



CAS_number =
CAS_supplemental =
ATC_prefix =
ATC_suffix =
ATC_supplemental =
PubChem = 213046
DrugBank =
chemical_formula =
C=28 | H=36 | N=4 | O=2 | S=1
molecular_weight = 492.676 g/mol
smiles = C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
legal_status =
routes_of_administration = oral

Lurasidone is a atypical antipsychotic by Dainippon Sumitomo Pharma (Japan). as of|2008, it is undergoing a Phase III clinical trial.

Lurasidone blocks D2- and 5-HT2A-receptors. It seems to cause less extrapyramidal side effects than current antipsychotics.

References

* cite journal
author = H. Spreitzer
date = June 9, 2008
title = Neue Wirkstoffe - Lurasidon
journal = Österreichische Apothekerzeitung
issue = 12/2008
pages = 616
language = German

* cite journal
author = Cole, P., Serradell, N., Rosa, E., Bolos, J.
title = Lurasidone hydrochloride. Dopamine D2/5-HT2A antagonist, Treatment of schizophrenia.
journal = Drugs of the Future
year = 2008
volume = 33
issue = 4
pages = 316-322


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Lurasidone — Général Nom IUPAC (3aR,4S,7R,7aS) 2 [((1R,2R) 2 {[4 (1,2 benzisothiazol 3 yl) pipérazin 1 yl]méthyl}cyclohexyl)méthyl]hexahydro 1H 4,7 méthanisoindol 1,3 dione …   Wikipédia en Français

  • lurasidone — noun A piperazine drug with potential applications in treating schizophrenia and bipolar disorder …   Wiktionary

  • Antipsychotic — Advertisement for Thorazine (chlorpromazine) from the 1950s[1] An antipsychotic (or neuroleptic) is a tranquilizing psychiatric medication primarily used to manage psychosis (including delusions or hallucinations, as well as disordered tho …   Wikipedia

  • Clozapine — Not to be confused with clonazepam or Klonopin. Clozapine Systematic (IUPAC) name …   Wikipedia

  • Trifluoperazine — Systematic (IUPAC) name 10 [3 (4 methylpiperazin 1 yl)propyl] 2 (trifluoromethyl) 10H phenothiazine Clinical data AHFS/ …   Wikipedia

  • Fluphenazine — Systematic (IUPAC) name 2 [4 [3 [2 (trifluoromethyl) 10H phenothiazin 10 yl]propyl]piperazin 1 yl]ethanol Clinical data …   Wikipedia

  • Olanzapine — Systematic (IUPAC) name 2 methyl 4 (4 methyl …   Wikipedia

  • Perphenazine — Systematic (IUPAC) name 2 [4 [3 (2 chloro 10H phenothiazin 10 yl) propyl]piperazin 1 yl]ethanol Clinical data AHFS/Drugs.com …   Wikipedia

  • Aripiprazole — Systematic (IUPAC) name 7 {4 [4 (2,3 dichlorophenyl)piperazin 1 yl]butoxy} 3,4 dihydroquinolin 2(1H) one Clinical data Trade names …   Wikipedia

  • Loxapine — Systematic (IUPAC) name 2 Chloro 11 (4 methylpiperazin 1 yl)dibenzo[b,f][1,4]oxazepine Clinical data AHFS/Drugs.com …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”