Furanolactone

A furanolactone is a heterocyclic chemical compound that contains both a lactone and a furan ring structure.

Examples include:

* Salvinorina, including the hallucinogenic compound salvinorin A
* Columbin, a potential chemopreventive compound
* Limonoids such as limonin, nomilin, and nomilinic acid

References

# Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE. (2006). Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring. "Bioorg Med Chem Lett" 16(12):3170-4.
# Kohno H, Maeda M, Tanino M, Tsukio Y, Ueda N, Wada K, Sugie S, Mori H, Tanaka T. (2002). A bitter diterpenoid furanolactone columbin from Calumbae Radix inhibits azoxymethane-induced rat colon carcinogenesis. "Cancer Lett" 183(2):131-9.
# Swaminathan K, Sinha UC, Ramakumar S, Bhatt RK, Sabata BK. (1989). Structure of columbin, a diterpenoid furanolactone from Tinospora cordifolia Miers. "Acta Crystallogr C" 45 ( Pt 2):300-3.