GM2 (ganglioside)

GM2 (ganglioside)

GM2 is a type of ganglioside.

It is associated with GM2 gangliosidoses (for example, Tay-Sachs disease.)cite journal |author=Guetta E, Peleg L |title=Rapid detection of fetal mendalian disorders: tay-sachs disease |journal=Methods Mol. Biol. |volume=444 |issue= |pages=147–59 |year=2008 |pmid=18425478 |doi=10.1007/978-1-59745-066-9_11 |url=http://dx.doi.org/10.1007/978-1-59745-066-9_11]

ee also

* Ganglioside GM2 activator protein

References

External links

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  • GM2 — can refer to: * General MIDI Level 2 * GM2 (ganglioside) …   Wikipedia

  • GM2-gangliosidosis, AB variant — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 32644 ICD10 = ICD9 = ICDO = OMIM = 272750 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 3016 MeshID = D049290 GM2 gangliosidosis, AB variant is a rare, autosomal recessive metabolic… …   Wikipedia

  • GM2 gangliosidoses — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 12916 DiseasesDB mult = DiseasesDB2|29469, DiseasesDB2|32644 ICD10 = ICD10|E|75|0|e|70 ICD9 = ICD9|330.1 ICDO = OMIM = 272800 OMIM mult = OMIM2|268800, OMIM2|272750 MedlinePlus =… …   Wikipedia

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  • GM2-gangliosidosis, type 1 — This disorder known as Tay Sachs disease (TSD) is concisely defined by OMIM (Online Mendelian Inheritance in Man) as “an autosomal recessive, progressive neurodegenerative disorder, which in the classic infantile form, is usually fatal by age 2… …   Medical dictionary

  • GM2 activator protein — a sphingolipid activator protein that binds GM2 ganglioside and related glycosphingolipids and presents them to hexosaminidase A for cleavage; it is necessary for enzyme activity. Deficiency results in GM2 gangliosidosis, AB variant …   Medical dictionary

  • GM2-gangliosidosis, B variant — This disorder known as Tay Sachs disease (TSD) is concisely defined by OMIM (Online Mendelian Inheritance in Man) as “an autosomal recessive, progressive neurodegenerative disorder, which in the classic infantile form, is usually fatal by age 2… …   Medical dictionary

  • Ganglioside — is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n acetylneuraminic acid, NANA) linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA …   Wikipedia

  • Ganglioside GM2 activator protein — is (GM2 AP) is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T cell activation through lipid presentation.This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents… …   Wikipedia

  • GM2-Aktivator — Bändermodell nach PDB  …   Deutsch Wikipedia

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