Venezuelan hemorrhagic fever

Venezuelan hemorrhagic fever

Taxobox
virus_group = v
familia = "Arenaviridae"
genus = "Arenavirus"
subdivision_ranks = Species
subdivision = "Guanarito virus"

Venezuelan hemorrhagic fever (VHF) is a zoonotic human illness, first identified in 1989, causing fever and malaise followed by hemorrhagic manifestations and convulsions. [cite journal |author=de Manzione N, Salas RA, Paredes H, "et al" |title=Venezuelan hemorrhagic fever: clinical and epidemiological studies of 165 cases |journal=Clin. Infect. Dis. |volume=26 |issue=2 |pages=308–13 |year=1998 |pmid=9502447 |doi= |url=] It is fatal in 30% of cases. The disease is endemic to Portuguesa state and Barinas state in Venezuela . The causal agent, Guanarito virus, is spread to humans through contact with the excreta of two rodent species: the short-tailed cane mouse ("Zygodontomys brevicauda"), and the cotton rat ("Sigmodon alstoni"). Human-to-human transmission of the virus has not been observed.

Guanarito virus is a member of the Arenavirus genus of negative single-stranded RNA viruses, and is closely related to a number of other rodent-borne emerging viruses that cause hemorrhagic fever in South America. [ [http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Arenavirus_Fact_Sheet.pdf Arenavirus Fact Sheet] , Centers for Disease Control.]

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