AKAP7

A kinase (PRKA) anchor protein 7, also known as AKAP7, is a human gene.cite web | title = Entrez Gene: AKAP7 A kinase (PRKA) anchor protein 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9465| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.cite web | title = Entrez Gene: AKAP7 A kinase (PRKA) anchor protein 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9465| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gold MG, Smith FD, Scott JD, Barford D |title=AKAP18 contains a phosphoesterase domain that binds AMP. |journal=J. Mol. Biol. |volume=375 |issue= 5 |pages= 1329-43 |year= 2008 |pmid= 18082768 |doi= 10.1016/j.jmb.2007.11.037
*cite journal | author=Bengrine A, Li J, Awayda MS |title=The A-kinase anchoring protein 15 regulates feedback inhibition of the epithelial Na+ channel. |journal=FASEB J. |volume=21 |issue= 4 |pages= 1189-201 |year= 2007 |pmid= 17244820 |doi= 10.1096/fj.06-6046com
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Brown RL, August SL, Williams CJ, Moss SB |title=AKAP7gamma is a nuclear RI-binding AKAP. |journal=Biochem. Biophys. Res. Commun. |volume=306 |issue= 2 |pages= 394-401 |year= 2003 |pmid= 12804576 |doi=
*cite journal | author=Alto NM, Soderling SH, Hoshi N, "et al." |title=Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 8 |pages= 4445-50 |year= 2003 |pmid= 12672969 |doi= 10.1073/pnas.0330734100
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Trotter KW, Fraser ID, Scott GK, "et al." |title=Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms. |journal=J. Cell Biol. |volume=147 |issue= 7 |pages= 1481-92 |year= 2000 |pmid= 10613906 |doi=
*cite journal | author=Fraser ID, Tavalin SJ, Lester LB, "et al." |title=A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events. |journal=EMBO J. |volume=17 |issue= 8 |pages= 2261-72 |year= 1998 |pmid= 9545239 |doi= 10.1093/emboj/17.8.2261

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