AIM2

Absent in melanoma 2, also known as AIM2, is a human gene.cite web | title = Entrez Gene: AIM2 absent in melanoma 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9447| accessdate = ]

PBB_Summary
section_title =
summary_text = AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.cite web | title = Entrez Gene: AIM2 absent in melanoma 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9447| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Landolfo S, Gariglio M, Gribaudo G, Lembo D |title=The Ifi 200 genes: an emerging family of IFN-inducible genes. |journal=Biochimie |volume=80 |issue= 8-9 |pages= 721-8 |year= 1999 |pmid= 9865494 |doi=
*cite journal | author=Woerner SM, Kloor M, Schwitalle Y, "et al." |title=The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers. |journal=Genes Chromosomes Cancer |volume=46 |issue= 12 |pages= 1080-9 |year= 2007 |pmid= 17726700 |doi= 10.1002/gcc.20493
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Chen IF, Ou-Yang F, Hung JY, "et al." |title=AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model. |journal=Mol. Cancer Ther. |volume=5 |issue= 1 |pages= 1-7 |year= 2006 |pmid= 16432157 |doi= 10.1158/1535-7163.MCT-05-0310
*cite journal | author=Cresswell KS, Clarke CJ, Jackson JT, "et al." |title=Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2. |journal=Biochem. Biophys. Res. Commun. |volume=326 |issue= 2 |pages= 417-24 |year= 2005 |pmid= 15582594 |doi= 10.1016/j.bbrc.2004.11.048
*cite journal | author=Liu G, Yu JS, Zeng G, "et al." |title=AIM-2: a novel tumor antigen is expressed and presented by human glioma cells. |journal=J. Immunother. |volume=27 |issue= 3 |pages= 220-6 |year= 2004 |pmid= 15076139 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Choubey D, Walter S, Geng Y, Xin H |title=Cytoplasmic localization of the interferon-inducible protein that is encoded by the AIM2 (absent in melanoma) gene from the 200-gene family. |journal=FEBS Lett. |volume=474 |issue= 1 |pages= 38-42 |year= 2000 |pmid= 10828447 |doi=
*cite journal | author=DeYoung KL, Ray ME, Su YA, "et al." |title=Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma. |journal=Oncogene |volume=15 |issue= 4 |pages= 453-7 |year= 1997 |pmid= 9242382 |doi= 10.1038/sj.onc.1201206

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