- RGS11
Regulator of G-protein signalling 11, also known as RGS11, is a human
gene .cite web | title = Entrez Gene: RGS11 regulator of G-protein signalling 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8786| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.cite web | title = Entrez Gene: RGS11 regulator of G-protein signalling 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8786| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Martin J, Han C, Gordon LA, "et al." |title=The sequence and analysis of duplication-rich human chromosome 16. |journal=Nature |volume=432 |issue= 7020 |pages= 988-94 |year= 2005 |pmid= 15616553 |doi= 10.1038/nature03187
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sierra DA, Gilbert DJ, Householder D, "et al." |title=Evolution of the regulators of G-protein signaling multigene family in mouse and human. |journal=Genomics |volume=79 |issue= 2 |pages= 177-85 |year= 2002 |pmid= 11829488 |doi= 10.1006/geno.2002.6693
*cite journal | author=Daniels RJ, Peden JF, Lloyd C, "et al." |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339-52 |year= 2001 |pmid= 11157797 |doi=
*cite journal | author=Snow BE, Betts L, Mangion J, "et al." |title=Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 11 |pages= 6489-94 |year= 1999 |pmid= 10339615 |doi=
*cite journal | author=Snow BE, Krumins AM, Brothers GM, "et al." |title=A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 22 |pages= 13307-12 |year= 1998 |pmid= 9789084 |doi=
*cite journal | author=Gold SJ, Ni YG, Dohlman HG, Nestler EJ |title=Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. |journal=J. Neurosci. |volume=17 |issue= 20 |pages= 8024-37 |year= 1997 |pmid= 9315921 |doi=PBB_Controls
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