NOSIP

Nitric oxide synthase interacting protein
Identifiers
Symbols	NOSIP; CGI-25
External IDs	MGI: 1913644 HomoloGene: 9315 GeneCards: NOSIP Gene
Gene Ontology Molecular function • protein binding Cellular component • nucleus • cytoplasm • cytosol Biological process • negative regulation of catalytic activity • nitric oxide metabolic process • regulation of nitric-oxide synthase activity • negative regulation of nitric-oxide synthase activity Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51070	66394
Ensembl	ENSG00000142546	ENSMUSG00000003421
UniProt	Q9Y314	n/a
RefSeq (mRNA)	NM_015953	NM_025533
RefSeq (protein)	NP_057037	NP_079809
Location (UCSC)	Chr 19: 50.06 – 50.08 Mb	Chr 7: 52.32 – 52.33 Mb
PubMed search	[1]	[2]

Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene.^[1][2][3]

References

1. ^ Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. 
2. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310876. 
3. ^ "Entrez Gene: NOSIP nitric oxide synthase interacting protein". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51070. 

Further reading

• Schleicher M, Brundin F, Gross S, et al. (2005). "Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton.". Mol. Cell. Biol. 25 (18): 8251–8. doi:10.1128/MCB.25.18.8251-8258.2005. PMC 1234313. PMID 16135813. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1234313. 
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413. 
• Dreyer J, Schleicher M, Tappe A, et al. (2005). "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity.". J. Neurosci. 24 (46): 10454–65. doi:10.1523/JNEUROSCI.2265-04.2004. PMID 15548660. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.