MBus or M-Bus can refer to:
- MBus (Nokia), a bus used with Nokia mobile phones
- MBus (SPARC), a computer bus designed for communication between high speed system components
- M-Bus, or Meter-Bus, a bus used for remote reading of gas or electricity meters
- Message Bus (Mbus), an Inter-process communication protocol developed by Universität Bremen and University College London for local coordination, specified in RFC 3259
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