- Theodor Boveri
Infobox Scientist
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birth_date =October 12 ,1862
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death_date =October 15 ,1915
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nationality = German
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field =genetics
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known_for =embryonic development Boveri-Sutton chromosome theory centrosome
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footnotes =Theodor Heinrich Boveri (
October 12 ,1862 –October 15 ,1915 ) was a Germanbiologist whose work withsea urchin s showed that it was necessary to have allchromosome s present in order for properembryonic development to take place. This discovery was an important part of theBoveri-Sutton chromosome theory . His other significant discovery was thecentrosome (1888), which he described as the "especial organ of cell division". Boveri also had discovered a phenomenon ofchromatin diminution do embryonic development of nematode Parascaris.He also reasoned that a cancerous tumor begins with a single cell in which the make up of its chromosomes becomes scrambled, causing the cells to divide uncontrollably.
It was only much later in the twentieth century that leading researchers came to believe that Boveri may have been correct.
References
*Citation | title = Theodor Boveri: The Life of a Great Biologist 1862-1915 | first = Fritz | last = Baltzer | year = 1967 | url = http://www.devbio.com/article.php?ch=7&id=75 | accessdate = 2007-07-22 . Extract published in Citation | last = Gilbert | first = SF | title = DevBio: a companion to Developmental Biology, 8th ed | year = 2006 | publisher = Sinauer Associates
*Citation | title = Concerning The Origin of Malignant Tumours | first = Theodor | last = Boveri | year = 2008 |journal =Journal of Cell Science |volume = 121 |issue = Supplement 1 | pages = 1–84 | url = http://jcs.biologists.org/cgi/content/full/121/Supplement_1/1 | doi = 10.1242/jcs.025742 | pmid = 18089652
*Citation | first = Florian | last = Maderspacher | year = 2008 | title = Theodor Boveri and the natural experiment |journal=Current Biology |volume= 18 | issue =7 | pages = R279–R286 | doi = 10.1016/j.cub.2008.02.061
*cite journal
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last=Satzinger
first=Helga
authorlink=
year=2008|month=Mar.title=Theodor and Marcella Boveri: chromosomes and cytoplasm in heredity and development
journal=Nat. Rev. Genet.
volume=9
issue=3
pages=231–8
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pmid = 18268510
doi = 10.1038/nrg2311
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*cite journal
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last=Laubichler
first=Manfred D
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coauthors=Davidson Eric H
year=2008|month=Feb.title=Boveri's long experiment: sea urchin merogones and the establishment of the role of nuclear chromosomes in development
journal=Dev. Biol.
volume=314
issue=1
pages=1–11
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pmid = 18163986
doi = 10.1016/j.ydbio.2007.11.024
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*cite journal
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last=Bignold
first=Leon P
authorlink=
coauthors=Coghlan Brian L D, Jersmann Hubertus P A
year=2006|month=Jul.title=Hansemann, Boveri, chromosomes and the gametogenesis-related theories of tumours
journal=Cell Biol. Int.
volume=30
issue=7
pages=640–4
publisher = | location =
pmid = 16753311
doi = 10.1016/j.cellbi.2006.04.002
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*cite journal
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last=Hardy
first=Paul A
authorlink=
coauthors=Zacharias Helmut
year=2005|month=Dec.title=Reappraisal of the Hansemann-Boveri hypothesis on the origin of tumors
journal=Cell Biol. Int.
volume=29
issue=12
pages=983–92
publisher = | location =
pmid = 16314117
doi = 10.1016/j.cellbi.2005.10.001
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*cite journal
quotes = yes
last=Wunderlich
first=Volker
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year=2002|month=Sep.title=JMM---past and present. Chromosomes and cancer: Theodor Boveri's predictions 100 years later
journal=J. Mol. Med.
volume=80
issue=9
pages=545–8
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pmid = 12226736
doi = 10.1007/s00109-002-0374-y
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*cite journal
quotes = yes
last=Manchester
first=K L
authorlink=
year=1997|month=Jul.title=Overlooked Nobel laureates
journal=Adler Museum bulletin
volume=23
issue=2
pages=20–1
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pmid = 11619485
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*cite journal
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last=Manchester
first=K
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year=1997|month=.title=The quest by three giants of science for an understanding of cancer
journal=Endeavour
volume=21
issue=2
pages=72–6
publisher = | location =
pmid = 9237430
bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote =doi=10.1016/S0160-9327(97)01030-2
*cite journal
quotes = yes
last=Moritz
first=K B
authorlink=
coauthors=Sauer H W
year=1996|month=Feb.title=Boveri's contributions to developmental biology--a challenge for today
journal=Int. J. Dev. Biol.
volume=40
issue=1
pages=27–47
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pmid = 8735909
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*cite journal
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last=BALTZER
first=F
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year=1964|month=May.title=Theodor Boveri
journal=Science
volume=144
issue=
pages=809–15
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pmid = 14149391
bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote =doi=10.1126/science.144.3620.809
*cite journal
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last=STERN
first=C
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year=1950|month=Sep.title=Boveri and the early days of genetics
journal=Nature
volume=166
issue=4219
pages=446
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pmid = 14775717
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Further reading
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External links
*Citation | url = http://www.biozentrum2.uni-wuerzburg.de/en/more_infos/theodor_boveri_1862-1915/ | first = Peter | last = Wolbert | title = Theodor Boveri (1862-1915) | accessdate=2007-07-22 | publisher = Biocenter of the University of Wuerzburg
* Fritz Baltzer. (1967). excerpt from [http://zygote.swarthmore.edu/fert6b.html Theodor Boveri: The life of a great biologist, 1862-1915] . University of California Press, Berkeley; pp. 85-97.
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