Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors — (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit Western societies. NRTIs inhibit the reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of the human immunodeficiency virus (HIV). The first … Wikipedia
Zidovudine — AZT redirects here. For other uses, see AZT (disambiguation). Zidovudine Systematic (IUPAC) name … Wikipedia
Antiretroviral drug — HAART redirects here. For UK estate agency Haart, see Spicerhaart. Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. When several such drugs, typically three or four, are taken in combination, the … Wikipedia
Didanosine — Systematic (IUPAC) name 9 [(2R,5S) 5 (hydroxymethyl)oxolan 2 yl] 6,9 dihydro 3H purin 6 one Clinical data AHFS/Drugs.c … Wikipedia
Zalcitabine — Systematic (IUPAC) name 4 amino 1 ((2R,5S) 5 (hydroxymethyl)tetrahydrofuran 2 yl)pyrimidin 2(1H) one Clinical data AHFS/Drugs.com … Wikipedia
Stavudine — Systematic (IUPAC) name 1 ((2R,5S) 5 (hydroxymethyl) 2,5 dihydrofuran 2 yl) 5 methylpyrimidine 2,4(1H,3H) dione Clinical data AHFS/Drugs.com … Wikipedia
Emtricitabine — Systematic (IUPAC) name 4 amino 5 fluoro 1 [(2S,5R) 2 (hydroxymethyl) 1,3 oxathiolan 5 yl] 1,2 dihydropyrimidin 2 one Clinical data … Wikipedia
Ritonavir — Systematic (IUPAC) name 1,3 thiazol 5 ylmethyl N [(2S,3S,5S) 3 hydroxy 5 [(2S) 3 methyl 2 {[methyl({[2 (propan 2 yl) 1,3 thiazol 4 yl]methyl})carbamoyl]amino}butanamido] 1,6 diphenylhexan 2 yl]carbamate … Wikipedia
Nevirapine — Systematic (IUPAC) name 11 cyclopropyl 4 methyl 5,11 d … Wikipedia
Nelfinavir — Systematic (IUPAC) name (3S,4aS,8aS) N tert butyl 2 [(2R,3R) 2 hydroxy 3 [(3 hydroxy 2 methylphenyl)formamido] 4 (phenylsulfanyl)butyl] decahydroisoquinoline 3 carboxamide … Wikipedia
