Acute chest syndrome

Acute chest syndrome

The acute chest syndrome is a vasoocclusive crisis of the pulmonary vasculature commonly seen in patients with sickle cell anemia. The crisis is often initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The acute chest syndrome is one of the most common causes of death for sickle cell patients. [Kumar, Abbas, Fausto. Robbins and Cotran: The Pathologic Basis of Disease, Page 631]

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