- WNT7B
Wingless-type MMTV integration site family, member 7B, also known as WNT7B, is a human
gene .cite web | title = Entrez Gene: WNT7B wingless-type MMTV integration site family, member 7B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7477| accessdate = ]PBB_Summary
section_title =
summary_text = The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 99% and 91% amino acid identity to the mouse and Xenopus Wnt7A proteins, respectively. Among members of the human WNT family, this protein is most similar to WNT7A protein (77.1% total amino acid identity). This gene may play important roles in the development and progression of gastric cancer, esophageal cancer, and pancreatic cancer.cite web | title = Entrez Gene: WNT7B wingless-type MMTV integration site family, member 7B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7477| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Smolich BD, McMahon JA, McMahon AP, Papkoff J |title=Wnt family proteins are secreted and associated with the cell surface. |journal=Mol. Biol. Cell |volume=4 |issue= 12 |pages= 1267–75 |year= 1994 |pmid= 8167409 |doi=
*cite journal | author=Huguet EL, McMahon JA, McMahon AP, "et al." |title=Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue. |journal=Cancer Res. |volume=54 |issue= 10 |pages= 2615–21 |year= 1994 |pmid= 8168088 |doi=
*cite journal | author=van Bokhoven H, Kissing J, Schepens M, "et al." |title=Assignment of WNT7B to human chromosome band 22q13 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=77 |issue= 3-4 |pages= 288–9 |year= 1997 |pmid= 9284940 |doi=
*cite journal | author=Tanaka K, Okabayashi K, Asashima M, "et al." |title=The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. |journal=Eur. J. Biochem. |volume=267 |issue= 13 |pages= 4300–11 |year= 2000 |pmid= 10866835 |doi=
*cite journal | author=Kirikoshi H, Sekihara H, Katoh M |title=Molecular cloning and characterization of human WNT7B. |journal=Int. J. Oncol. |volume=19 |issue= 4 |pages= 779–83 |year= 2001 |pmid= 11562755 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Capurro MI, Shi W, Sandal S, Filmus J |title=Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growth. |journal=J. Biol. Chem. |volume=280 |issue= 50 |pages= 41201–6 |year= 2006 |pmid= 16227623 |doi= 10.1074/jbc.M507004200PBB_Controls
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