- TENC1
Tensin like C1 domain containing phosphatase (tensin 2), also known as TENC1, is a human
gene .cite web | title = Entrez Gene: TENC1 tensin like C1 domain containing phosphatase (tensin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23371| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.cite web | title = Entrez Gene: TENC1 tensin like C1 domain containing phosphatase (tensin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23371| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kikuno R, Nagase T, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=
*cite journal | author=Chen H, Duncan IC, Bozorgchami H, Lo SH |title=Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 2 |pages= 733–8 |year= 2002 |pmid= 11792844 |doi= 10.1073/pnas.022518699
*cite journal | author=Hafizi S, Alindri F, Karlsson R, Dahlbäck B |title=Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin. |journal=Biochem. Biophys. Res. Commun. |volume=299 |issue= 5 |pages= 793–800 |year= 2003 |pmid= 12470648 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Calderwood DA, Fujioka Y, de Pereda JM, "et al." |title=Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 5 |pages= 2272–7 |year= 2003 |pmid= 12606711 |doi= 10.1073/pnas.262791999
*cite journal | author=Hu Y, Fang X, Dunham SM, "et al." |title=90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling. |journal=J. Biol. Chem. |volume=279 |issue= 28 |pages= 29325–35 |year= 2004 |pmid= 15117958 |doi= 10.1074/jbc.M311144200
*cite journal | author=Hafizi S, Ibraimi F, Dahlbäck B |title=C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration. |journal=FASEB J. |volume=19 |issue= 8 |pages= 971–3 |year= 2006 |pmid= 15817639 |doi= 10.1096/fj.04-2532fje
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Yam JW, Ko FC, Chan CY, "et al." |title=Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma. |journal=Hepatology |volume=44 |issue= 4 |pages= 881–90 |year= 2006 |pmid= 17006924 |doi= 10.1002/hep.21339PBB_Controls
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