- SLC14A2
Solute carrier family 14 (urea transporter), member 2, also known as SLC14A2, is a human
gene .cite web | title = Entrez Gene: SLC14A2 solute carrier family 14 (urea transporter), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8170| accessdate = ]PBB_Summary
section_title =
summary_text = In mammalian cells, urea is the chief end-product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. Thus, the plasma membrane of erythrocytes and some renal epithelial cells exhibit an elevated urea permeability that is mediated by highly selective urea transporters. In mammals, 2 urea transporters have been identified: the renal tubular urea transporter, UT2, and the erythrocyte urea transporter, UT11 (SLC14A1; MIM 111000). [supplied by OMIM] cite web | title = Entrez Gene: SLC14A2 solute carrier family 14 (urea transporter), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8170| accessdate = ]ee also
*
Solute carrier family References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Smith CP, Fenton RA |title=Genomic organization of the mammalian SLC14a2 urea transporter genes. |journal=J. Membr. Biol. |volume=212 |issue= 2 |pages= 109–17 |year= 2007 |pmid= 17264986 |doi= 10.1007/s00232-006-0870-z
*cite journal | author=Olives B, Neau P, Bailly P, "et al." |title=Cloning and functional expression of a urea transporter from human bone marrow cells. |journal=J. Biol. Chem. |volume=269 |issue= 50 |pages= 31649–52 |year= 1995 |pmid= 7989337 |doi=
*cite journal | author=Olivès B, Martial S, Mattei MG, "et al." |title=Molecular characterization of a new urea transporter in the human kidney. |journal=FEBS Lett. |volume=386 |issue= 2-3 |pages= 156–60 |year= 1996 |pmid= 8647271 |doi=
*cite journal | author=Bradford AD, Terris JM, Ecelbarger CA, "et al." |title=97- and 117-kDa forms of collecting duct urea transporter UT-A1 are due to different states of glycosylation. |journal=Am. J. Physiol. Renal Physiol. |volume=281 |issue= 1 |pages= F133–43 |year= 2001 |pmid= 11399654 |doi=
*cite journal | author=Bagnasco SM, Peng T, Janech MG, "et al." |title=Cloning and characterization of the human urea transporter UT-A1 and mapping of the human Slc14a2 gene. |journal=Am. J. Physiol. Renal Physiol. |volume=281 |issue= 3 |pages= F400–6 |year= 2001 |pmid= 11502588 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jung JY, Madsen KM, Han KH, "et al." |title=Expression of urea transporters in potassium-depleted mouse kidney. |journal=Am. J. Physiol. Renal Physiol. |volume=285 |issue= 6 |pages= F1210–24 |year= 2003 |pmid= 12952854 |doi= 10.1152/ajprenal.00111.2003
*cite journal | author=Smith CP, Potter EA, Fenton RA, Stewart GS |title=Characterization of a human colonic cDNA encoding a structurally novel urea transporter, hUT-A6. |journal=Am. J. Physiol., Cell Physiol. |volume=287 |issue= 4 |pages= C1087–93 |year= 2004 |pmid= 15189812 |doi= 10.1152/ajpcell.00363.2003
*cite journal | author=Damiano AE, Zotta E, Ibarra C |title=Functional and molecular expression of AQP9 channel and UT-A transporter in normal and preeclamptic human placentas. |journal=Placenta |volume=27 |issue= 11-12 |pages= 1073–81 |year= 2006 |pmid= 16480766 |doi= 10.1016/j.placenta.2005.11.014
*cite journal | author=Hong X, Xing H, Yu Y, "et al." |title=Genetic polymorphisms of the urea transporter gene are associated with antihypertensive response to nifedipine GITS. |journal=Methods and findings in experimental and clinical pharmacology |volume=29 |issue= 1 |pages= 3–10 |year= 2007 |pmid= 17344938 |doi= 10.1358/mf.2007.29.1.1063490PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.
