- WNT2B
Wingless-type MMTV integration site family, member 2B, also known as WNT2B, is a human
gene .cite web | title = Entrez Gene: WNT2B wingless-type MMTV integration site family, member 2B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7482| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.cite web | title = Entrez Gene: WNT2B wingless-type MMTV integration site family, member 2B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7482| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Katoh M |title=WNT2B: comparative integromics and clinical applications (Review). |journal=Int. J. Mol. Med. |volume=16 |issue= 6 |pages= 1103–8 |year= 2006 |pmid= 16273293 |doi=
*cite journal | author=Smolich BD, McMahon JA, McMahon AP, Papkoff J |title=Wnt family proteins are secreted and associated with the cell surface. |journal=Mol. Biol. Cell |volume=4 |issue= 12 |pages= 1267–75 |year= 1994 |pmid= 8167409 |doi=
*cite journal | author=Katoh M, Hirai M, Sugimura T, Terada M |title=Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family. |journal=Oncogene |volume=13 |issue= 4 |pages= 873–6 |year= 1996 |pmid= 8761309 |doi=
*cite journal | author=Bergstein I, Eisenberg LM, Bhalerao J, "et al." |title=Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. |journal=Genomics |volume=46 |issue= 3 |pages= 450–8 |year= 1998 |pmid= 9441749 |doi= 10.1006/geno.1997.5041
*cite journal | author=Katoh M, Kirikoshi H, Saitoh T, "et al." |title=Alternative splicing of the WNT-2B/WNT-13 gene. |journal=Biochem. Biophys. Res. Commun. |volume=275 |issue= 1 |pages= 209–16 |year= 2000 |pmid= 10944466 |doi= 10.1006/bbrc.2000.3252
*cite journal | author=Katoh M |title=Differential regulation of WNT2 and WNT2B expression in human cancer. |journal=Int. J. Mol. Med. |volume=8 |issue= 6 |pages= 657–60 |year= 2002 |pmid= 11712082 |doi=
*cite journal | author=Yarden RI, Brody LC |title=Identification of proteins that interact with BRCA1 by Far-Western library screening. |journal=J. Cell. Biochem. |volume=83 |issue= 4 |pages= 521–31 |year= 2002 |pmid= 11746496 |doi=
*cite journal | author=Ricken A, Lochhead P, Kontogiannea M, Farookhi R |title=Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs. |journal=Endocrinology |volume=143 |issue= 7 |pages= 2741–9 |year= 2002 |pmid= 12072409 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Katoh M |title=Molecular evolution of Wnt2b orthologs. |journal=Int. J. Oncol. |volume=26 |issue= 4 |pages= 1135–9 |year= 2005 |pmid= 15754012 |doi=
*cite journal | author=Struewing IT, Toborek A, Mao CD |title=Mitochondrial and nuclear forms of Wnt13 are generated via alternative promoters, alternative RNA splicing, and alternative translation start sites. |journal=J. Biol. Chem. |volume=281 |issue= 11 |pages= 7282–93 |year= 2006 |pmid= 16407296 |doi= 10.1074/jbc.M511182200PBB_Controls
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