SH2D1B

SH2 domain containing 1B, also known as SH2D1B, is a human gene.cite web | title = Entrez Gene: SH2D1B SH2 domain containing 1B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117157| accessdate = ]

PBB_Summary
section_title =
summary_text = By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001). [supplied by OMIM] cite web | title = Entrez Gene: SH2D1B SH2 domain containing 1B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117157| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Morra M, Howie D, Grande MS, "et al." |title=X-linked lymphoproliferative disease: a progressive immunodeficiency. |journal=Annu. Rev. Immunol. |volume=19 |issue= |pages= 657–82 |year= 2001 |pmid= 11244050 |doi= 10.1146/annurev.immunol.19.1.657
*cite journal | author=Veillette A, Latour S |title=The SLAM family of immune-cell receptors. |journal=Curr. Opin. Immunol. |volume=15 |issue= 3 |pages= 277–85 |year= 2004 |pmid= 12787752 |doi=
*cite journal | author=Thompson AD, Braun BS, Arvand A, "et al." |title=EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene. |journal=Oncogene |volume=13 |issue= 12 |pages= 2649–58 |year= 1997 |pmid= 9000139 |doi=
*cite journal | author=Morra M, Lu J, Poy F, "et al." |title=Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells. |journal=EMBO J. |volume=20 |issue= 21 |pages= 5840–52 |year= 2001 |pmid= 11689425 |doi= 10.1093/emboj/20.21.5840
*cite journal | author=Tangye SG, van de Weerdt BC, Avery DT, Hodgkin PD |title=CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2. |journal=Eur. J. Immunol. |volume=32 |issue= 6 |pages= 1640–9 |year= 2002 |pmid= 12115647 |doi= 10.1002/1521-4141(200206)32:6<1640::AID-IMMU1640>3.0.CO;2-S |doilabel=10.1002/1521-4141(200206)32:61640::AID-IMMU16403.0.CO;2-S
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Eissmann P, Watzl C |title=Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cells. |journal=J. Immunol. |volume=177 |issue= 5 |pages= 3170–7 |year= 2006 |pmid= 16920955 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes