SCGB3A2

SCGB3A2

Secretoglobin, family 3A, member 2, also known as SCGB3A2, is a human gene.cite web | title = Entrez Gene: SCGB3A2 secretoglobin, family 3A, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117156| accessdate = ]

PBB_Summary
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summary_text = In addition to regulating thyroid-specific expression of genes, thyroid transcription factor (TITF1; MIM 600635) controls the transcription of genes specifically expressed in lung, such as surfactant proteins (e.g., SFTPA1; MIM 178630) and uteroglobin (UGB; MIM 192020). Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs (Kimura et al., 1996). The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1. [supplied by OMIM] cite web | title = Entrez Gene: SCGB3A2 secretoglobin, family 3A, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117156| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kimura S, Hara Y, Pineau T, "et al." |title=The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. |journal=Genes Dev. |volume=10 |issue= 1 |pages= 60–9 |year= 1996 |pmid= 8557195 |doi=
*cite journal | author=Wattiez R, Hermans C, Cruyt C, "et al." |title=Human bronchoalveolar lavage fluid protein two-dimensional database: study of interstitial lung diseases. |journal=Electrophoresis |volume=21 |issue= 13 |pages= 2703–12 |year= 2001 |pmid= 10949149 |doi= 10.1002/1522-2683(20000701)21:13<2703::AID-ELPS2703>3.0.CO;2-W |doilabel=10.1002/1522-2683(20000701)21:132703::AID-ELPS27033.0.CO;2-W
*cite journal | author=Niimi T, Keck-Waggoner CL, Popescu NC, "et al." |title=UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor. |journal=Mol. Endocrinol. |volume=15 |issue= 11 |pages= 2021–36 |year= 2002 |pmid= 11682631 |doi=
*cite journal | author=Niimi T, Munakata M, Keck-Waggoner CL, "et al." |title=A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma. |journal=Am. J. Hum. Genet. |volume=70 |issue= 3 |pages= 718–25 |year= 2002 |pmid= 11813133 |doi=
*cite journal | author=Porter D, Lahti-Domenici J, Torres-Arzayus M, "et al." |title=Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. |journal=Mech. Dev. |volume=114 |issue= 1-2 |pages= 201–4 |year= 2003 |pmid= 12175512 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bin LH, Nielson LD, Liu X, "et al." |title=Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair. |journal=J. Immunol. |volume=171 |issue= 2 |pages= 924–30 |year= 2003 |pmid= 12847263 |doi=
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Srisodsai A, Kurotani R, Chiba Y, "et al." |title=Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1. |journal=J. Biol. Chem. |volume=279 |issue= 52 |pages= 54358–68 |year= 2005 |pmid= 15485815 |doi= 10.1074/jbc.M405331200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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  • Secretoglobin — A family of small disulfide linked dimeric proteins found only in mammals. Family members:* Uteroglobin ( SCGB1A1) * Lacryglobin or Mammoglobin B (SCGB2A1) * Mammaglobin1 (SCGB2A2) * SCGB3A2 * * Fel d 1 …   Wikipedia

  • SCGB3A1 — Secretoglobin, family 3A, member 1, also known as SCGB3A1, is a human gene.cite web | title = Entrez Gene: SCGB3A1 secretoglobin, family 3A, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=92304|… …   Wikipedia

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