Alpha-v beta-5

Alpha-v beta-5

αVβ5 is a type of integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. However, recent studies [ [http://www.jci.org/cgi/reprint/110/7/913.pdf Endothelial integrins and angiogenesis: not so simple anymore] ] indicate that it actually inhibits angiogenesis.

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