RBBP5

Retinoblastoma binding protein 5, also known as RBBP5, is a human gene.cite web | title = Entrez Gene: RBBP5 retinoblastoma binding protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5929| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B.cite web | title = Entrez Gene: RBBP5 retinoblastoma binding protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5929| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Saijo M, Sakai Y, Kishino T, "et al." |title=Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping. |journal=Genomics |volume=27 |issue= 3 |pages= 511–9 |year= 1995 |pmid= 7558034 |doi= 10.1006/geno.1995.1084
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=
*cite journal | author=Suzuki Y, Tsunoda T, Sese J, "et al." |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes. |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.164001
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Goo YH, Sohn YC, Kim DH, "et al." |title=Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 1 |pages= 140–9 |year= 2003 |pmid= 12482968 |doi=
*cite journal | author=Hughes CM, Rozenblatt-Rosen O, Milne TA, "et al." |title=Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. |journal=Mol. Cell |volume=13 |issue= 4 |pages= 587–97 |year= 2004 |pmid= 14992727 |doi=
*cite journal | author=Yokoyama A, Wang Z, Wysocka J, "et al." |title=Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. |journal=Mol. Cell. Biol. |volume=24 |issue= 13 |pages= 5639–49 |year= 2004 |pmid= 15199122 |doi= 10.1128/MCB.24.13.5639-5649.2004
*cite journal | author=Dou Y, Milne TA, Tackett AJ, "et al." |title=Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. |journal=Cell |volume=121 |issue= 6 |pages= 873–85 |year= 2005 |pmid= 15960975 |doi= 10.1016/j.cell.2005.04.031
*cite journal | author=Scacheri PC, Davis S, Odom DT, "et al." |title=Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. |journal=PLoS Genet. |volume=2 |issue= 4 |pages= e51 |year= 2006 |pmid= 16604156 |doi= 10.1371/journal.pgen.0020051
*cite journal | author=Higa LA, Wu M, Ye T, "et al." |title=CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. |journal=Nat. Cell Biol. |volume=8 |issue= 11 |pages= 1277–83 |year= 2006 |pmid= 17041588 |doi= 10.1038/ncb1490
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

PBB_Controls
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require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes