COL5A3

COL5A3

Collagen, type V, alpha 3, also known as COL5A3, is a human gene.cite web | title = Entrez Gene: COL5A3 collagen, type V, alpha 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50509| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages.cite web | title = Entrez Gene: COL5A3 collagen, type V, alpha 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50509| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=van der Rest M, Garrone R |title=Collagen family of proteins. |journal=FASEB J. |volume=5 |issue= 13 |pages= 2814–23 |year= 1991 |pmid= 1916105 |doi=
*cite journal | author=Fichard A, Kleman JP, Ruggiero F |title=Another look at collagen V and XI molecules. |journal=Matrix Biol. |volume=14 |issue= 7 |pages= 515–31 |year= 1996 |pmid= 8535602 |doi=
*cite journal | author=Mann K |title=Isolation of the alpha 3-chain of human type V collagen and characterization by partial sequencing. |journal=Biol. Chem. Hoppe-Seyler |volume=373 |issue= 2 |pages= 69–75 |year= 1992 |pmid= 1571108 |doi=
*cite journal | author=Niyibizi C, Fietzek PP, van der Rest M |title=Human placenta type V collagens. Evidence for the existence of an alpha 1(V) alpha 2(V) alpha 3(V) collagen molecule. |journal=J. Biol. Chem. |volume=259 |issue= 22 |pages= 14170–4 |year= 1984 |pmid= 6501291 |doi=
*cite journal | author=Abedin MZ, Ayad S, Weiss JB |title=Isolation and native characterization of cysteine-rich collagens from bovine placental tissues and uterus and their relationship to types IV and V collagens. |journal=Biosci. Rep. |volume=2 |issue= 7 |pages= 493–502 |year= 1982 |pmid= 7115902 |doi=
*cite journal | author=Rhodes RK, Miller EJ |title=Evidence for the existence of an alpha 1(V) alpha 2(V) alpha 3(V) collagen molecule in human placental tissue. |journal=Coll. Relat. Res. |volume=1 |issue= 4 |pages= 337–43 |year= 1982 |pmid= 7346227 |doi=
*cite journal | author=Kypreos KE, Sonenshein GE |title=Basic fibroblast growth factor decreases type V/XI collagen expression in cultured bovine aortic smooth muscle cells. |journal=J. Cell. Biochem. |volume=68 |issue= 2 |pages= 247–58 |year= 1998 |pmid= 9443080 |doi=
*cite journal | author=Imamura Y, Scott IC, Greenspan DS |title=The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains. |journal=J. Biol. Chem. |volume=275 |issue= 12 |pages= 8749–59 |year= 2000 |pmid= 10722718 |doi=
*cite journal | author=Chanut-Delalande H, Fichard A, Bernocco S, "et al." |title=Control of heterotypic fibril formation by collagen V is determined by chain stoichiometry. |journal=J. Biol. Chem. |volume=276 |issue= 26 |pages= 24352–9 |year= 2001 |pmid= 11423559 |doi=
*cite journal | author=Gopalakrishnan B, Wang WM, Greenspan DS |title=Biosynthetic processing of the Pro-alpha1(V)Pro-alpha2(V)Pro-alpha3(V) procollagen heterotrimer. |journal=J. Biol. Chem. |volume=279 |issue= 29 |pages= 30904–12 |year= 2004 |pmid= 15136578 |doi= 10.1074/jbc.M402252200
*cite journal | author=Nagato H, Matsuo N, Sumiyoshi H, "et al." |title=The transcription factor CCAAT-binding factor CBF/NF-Y and two repressors regulate the core promoter of the human pro-alpha3(V) collagen gene (COL5A3). |journal=J. Biol. Chem. |volume=279 |issue= 45 |pages= 46373–83 |year= 2004 |pmid= 15316020 |doi= 10.1074/jbc.M406069200

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Collagen — Tropocollagen triple helix Collagen /ˈkɒlədʒɨn/ is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals.[1] It is the main component of connectiv …   Wikipedia

  • Keratin — Not to be confused with kerogen, carotene, chitin, or creatine. Microscopy of keratin filaments inside cells. Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human… …   Wikipedia

  • Extracellular matrix — Illustration depicting extracellular matrix (basement membrane and interstitial matrix) in relation to epithelium, endothelium and connective tissue Latin …   Wikipedia

  • Cytokeratin — Keratin intermediate filaments in epithelial cells (red stain). Cytokeratins are proteins of keratin containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The term cytokeratin began to be used in the… …   Wikipedia

  • Decorin — PDB rendering based on 1xcd …   Wikipedia

  • Type-IV collagen — is a type of collagen found primarily in the basal lamina. The type IV collagen C4 domain at the C terminus is not removed in post translational processing, and the fibers link head to head, rather than in parallel. Also, type IV lacks the… …   Wikipedia

  • Type-II collagen — collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) Identifiers Symbol COL2A1 Alt. symbols SEDC Entrez …   Wikipedia

  • Type-I collagen — collagen, type I, alpha 1 Identifiers Symbol COL1A1 Entrez 1277 HUGO …   Wikipedia

  • Type-V collagen — is a form of fibrillar [cite journal |author=Wenstrup RJ, Florer JB, Brunskill EW, Bell SM, Chervoneva I, Birk DE |title=Type V collagen controls the initiation of collagen fibril assembly |journal=J. Biol. Chem. |volume=279 |issue=51… …   Wikipedia

  • COL1A2 — Collagen, type I, alpha 2 Identifiers Symbols COL1A2; OI4 External IDs OMIM: …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”