TARP (gene)

TCR gamma alternate reading frame protein, also known as TARP, is a human gene.cite web | title = Entrez Gene: TARP TCR gamma alternate reading frame protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=445347| accessdate = ]

PBB_Summary
section_title =
summary_text = In some non-lymphoid tissues, the unrearranged T cell receptor gamma (TRG@) locus is expressed. The resulting transcript contains a subset of the TRG@ gene segments and is shorter than TRG@ transcripts expressed in lymphoid tissues. This RefSeq record represents the unrearranged TRG@ locus transcript; the complete TRG@ locus is represented by the genomic RefSeq NG_001336. The transcript represented by this RefSeq has two open reading frames (ORFs) that encode different proteins. The downstream ORF is in the same frame as TRG@ and its protein product is similar to TRG@ proteins. The upstream ORF uses a different reading frame and encodes a novel protein.cite web | title = Entrez Gene: TARP TCR gamma alternate reading frame protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=445347| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yoshikai Y, Toyonaga B, Koga Y, "et al." |title=Repertoire of the human T cell gamma genes: high frequency of nonfunctional transcripts in thymus and mature T cells. |journal=Eur. J. Immunol. |volume=17 |issue= 1 |pages= 119–26 |year= 1987 |pmid= 2949984 |doi=
*cite journal | author=Krangel MS, Band H, Hata S, "et al." |title=Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes. |journal=Science |volume=237 |issue= 4810 |pages= 64–7 |year= 1987 |pmid= 2955517 |doi=
*cite journal | author=Tighe L, Forster A, Clark DM, "et al." |title=Unusual forms of T cell gamma mRNA in a human T cell leukemia cell line: implications for gamma gene expression. |journal=Eur. J. Immunol. |volume=17 |issue= 12 |pages= 1729–36 |year= 1988 |pmid= 2961573 |doi=
*cite journal | author=Littman DR, Newton M, Crommie D, "et al." |title=Characterization of an expressed CD3-associated Ti gamma-chain reveals C gamma domain polymorphism. |journal=Nature |volume=326 |issue= 6108 |pages= 85–8 |year= 1987 |pmid= 3102973 |doi= 10.1038/326085a0
*cite journal | author=Pelicci PG, Subar M, Weiss A, "et al." |title=Molecular diversity of the human T-gamma constant region genes. |journal=Science |volume=237 |issue= 4818 |pages= 1051–5 |year= 1987 |pmid= 3112943 |doi=
*cite journal | author=Essand M, Vasmatzis G, Brinkmann U, "et al." |title=High expression of a specific T-cell receptor gamma transcript in epithelial cells of the prostate. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 16 |pages= 9287–92 |year= 1999 |pmid= 10430935 |doi=
*cite journal | author=Wolfgang CD, Essand M, Vincent JJ, "et al." |title=TARP: a nuclear protein expressed in prostate and breast cancer cells derived from an alternate reading frame of the T cell receptor gamma chain locus. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 17 |pages= 9437–42 |year= 2000 |pmid= 10931945 |doi= 10.1073/pnas.160270597
*cite journal | author=Wolfgang CD, Essand M, Lee B, Pastan I |title=T-cell receptor gamma chain alternate reading frame protein (TARP) expression in prostate cancer cells leads to an increased growth rate and induction of caveolins and amphiregulin. |journal=Cancer Res. |volume=61 |issue= 22 |pages= 8122–6 |year= 2001 |pmid= 11719440 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cheng WS, Giandomenico V, Pastan I, Essand M |title=Characterization of the androgen-regulated prostate-specific T cell receptor gamma-chain alternate reading frame protein (TARP) promoter. |journal=Endocrinology |volume=144 |issue= 8 |pages= 3433–40 |year= 2003 |pmid= 12865322 |doi=
*cite journal | author=Maeda H, Nagata S, Wolfgang CD, "et al." |title=The T cell receptor gamma chain alternate reading frame protein (TARP), a prostate-specific protein localized in mitochondria. |journal=J. Biol. Chem. |volume=279 |issue= 23 |pages= 24561–8 |year= 2004 |pmid= 15150260 |doi= 10.1074/jbc.M402492200

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