ASCL2

Achaete-scute complex homolog 2 (Drosophila), also known as ASCL2, is an imprinted human gene.cite web | title = Entrez Gene: ASCL2 achaete-scute complex homolog 2 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=430| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.cite web | title = Entrez Gene: ASCL2 achaete-scute complex homolog 2 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=430| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Miyamoto T, Jinno Y, Sasaki T, "et al." |title=Genomic cloning and localization to chromosome 11p15.5 of the human achaete-scute homolog 2 (ASCL2). |journal=Cytogenet. Cell Genet. |volume=73 |issue= 4 |pages= 312–4 |year= 1996 |pmid= 8751384 |doi=
*cite journal | author=Alders M, Hodges M, Hadjantonakis AK, "et al." |title=The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. |journal=Hum. Mol. Genet. |volume=6 |issue= 6 |pages= 859–67 |year= 1997 |pmid= 9175731 |doi=
*cite journal | author=Miyamoto T, Jinno Y, Miura K, "et al." |title=A SacII polymorphism in the human ASCL2 (HASH2) gene region. |journal=J. Hum. Genet. |volume=43 |issue= 1 |pages= 69–70 |year= 1998 |pmid= 9610003 |doi=
*cite journal | author=Onions J, Hermann S, Grundström T |title=A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors. |journal=Biochemistry |volume=39 |issue= 15 |pages= 4366–74 |year= 2000 |pmid= 10757985 |doi=
*cite journal | author=Westerman BA, Poutsma A, Looijenga LH, "et al." |title=The Human Achaete Scute Homolog 2 gene contains two promotors, generating overlapping transcripts and encoding two proteins with different nuclear localization. |journal=Placenta |volume=22 |issue= 6 |pages= 511–8 |year= 2001 |pmid= 11440538 |doi= 10.1053/plac.2001.0695
*cite journal | author=Miyamoto T, Hasuike S, Jinno Y, "et al." |title=The human ASCL2 gene escaping genomic imprinting and its expression pattern. |journal=J. Assist. Reprod. Genet. |volume=19 |issue= 5 |pages= 240–4 |year= 2002 |pmid= 12099555 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Goo YH, Sohn YC, Kim DH, "et al." |title=Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 1 |pages= 140–9 |year= 2003 |pmid= 12482968 |doi=
*cite journal | author=Jiang B, Mendelson CR |title=USF1 and USF2 mediate inhibition of human trophoblast differentiation and CYP19 gene expression by Mash-2 and hypoxia. |journal=Mol. Cell. Biol. |volume=23 |issue= 17 |pages= 6117–28 |year= 2003 |pmid= 12917334 |doi=
*cite journal | author=Koide S, Yoshida I, Tsuji A, Matsuda Y |title=The expression of proprotein convertase PACE4 is highly regulated by Hash-2 in placenta: possible role of placenta-specific basic helix-loop-helix transcription factor, human achaete-scute homologue-2. |journal=J. Biochem. |volume=134 |issue= 3 |pages= 433–40 |year= 2004 |pmid= 14561729 |doi=
*cite journal | author=Jubb AM, Chalasani S, Frantz GD, "et al." |title=Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia. |journal=Oncogene |volume=25 |issue= 24 |pages= 3445–57 |year= 2006 |pmid= 16568095 |doi= 10.1038/sj.onc.1209382
*cite journal | author=Shahib MN, Martaadisoebrata D, Kato H |title=Detection of HASH2 (ASCL2) gene expression in gestational trophoblastic disease. |journal=The Journal of reproductive medicine |volume=51 |issue= 11 |pages= 892–6 |year= 2007 |pmid= 17165436 |doi=

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