GRIK3

GRIK3

Glutamate receptor, ionotropic, kainate 3, also known as GRIK3, is a human gene.cite web | title = Entrez Gene: GRIK3 glutamate receptor, ionotropic, kainate 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2899| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a protein that belongs to the ligand-gated ionic channel family. It can coassemble with either GRIK4 or GRIK5 to form heteromeric receptors and acts as an excitatory neurotransmitter at many synapses in the central nervous system. RNA editing in the mRNA has been reported.cite web | title = Entrez Gene: GRIK3 glutamate receptor, ionotropic, kainate 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2899| accessdate = ]

ee also

* Kainate receptor

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nutt SL, Hoo KH, Rampersad V, "et al." |title=Molecular characterization of the human EAA5 (GluR7) receptor: a high-affinity kainate receptor with novel potential RNA editing sites. |journal=Recept. Channels |volume=2 |issue= 4 |pages= 315–26 |year= 1995 |pmid= 7719709 |doi=
*cite journal | author=Puranam RS, Eubanks JH, Heinemann SF, McNamara JO |title=Chromosomal localization of gene for human glutamate receptor subunit-7. |journal=Somat. Cell Mol. Genet. |volume=19 |issue= 6 |pages= 581–8 |year= 1994 |pmid= 8128318 |doi=
*cite journal | author=Roche KW, Raymond LA, Blackstone C, Huganir RL |title=Transmembrane topology of the glutamate receptor subunit GluR6. |journal=J. Biol. Chem. |volume=269 |issue= 16 |pages= 11679–82 |year= 1994 |pmid= 8163463 |doi=
*cite journal | author=Ripellino JA, Neve RL, Howe JR |title=Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum. |journal=Neuroscience |volume=82 |issue= 2 |pages= 485–97 |year= 1998 |pmid= 9466455 |doi=
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Schiffer HH, Swanson GT, Masliah E, Heinemann SF |title=Unequal expression of allelic kainate receptor GluR7 mRNAs in human brains. |journal=J. Neurosci. |volume=20 |issue= 24 |pages= 9025–33 |year= 2001 |pmid= 11124978 |doi=
*cite journal | author=Enz R |title=The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7. |journal=FEBS Lett. |volume=514 |issue= 2-3 |pages= 184–8 |year= 2002 |pmid= 11943148 |doi=
*cite journal | author=Begni S, Popoli M, Moraschi S, "et al." |title=Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia. |journal=Mol. Psychiatry |volume=7 |issue= 4 |pages= 416–8 |year= 2002 |pmid= 11986986 |doi= 10.1038/sj.mp.4000987
*cite journal | author=Delorme R, Krebs MO, Chabane N, "et al." |title=Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder. |journal=Neuroreport |volume=15 |issue= 4 |pages= 699–702 |year= 2004 |pmid= 15094479 |doi=
*cite journal | author=Preuss UW, Zill P, Koller G, "et al." |title=Ionotropic glutamate receptor gene GRIK3 SER310ALA functional polymorphism is related to delirium tremens in alcoholics. |journal=Pharmacogenomics J. |volume=6 |issue= 1 |pages= 34–41 |year= 2006 |pmid= 16314883 |doi= 10.1038/sj.tpj.6500343
*cite journal | author=Samochowiec J, Grzywacz A, Kucharska-Mazur J, "et al." |title=Family-based and case-control association studies of glutamate receptor GRIK3 Ser310Ala polymorphism in Polish patients and families with alcohol dependence. |journal=Neurosci. Lett. |volume=396 |issue= 2 |pages= 159–62 |year= 2006 |pmid= 16356644 |doi= 10.1016/j.neulet.2005.11.030
*cite journal | author=Schiffer HH, Heinemann SF |title=Association of the human kainate receptor GluR7 gene (GRIK3) with recurrent major depressive disorder. |journal=Am. J. Med. Genet. B Neuropsychiatr. Genet. |volume=144 |issue= 1 |pages= 20–6 |year= 2007 |pmid= 16958029 |doi= 10.1002/ajmg.b.30374
*cite journal | author=Kim JM, Lee KH, Jeon YJ, "et al." |title=Identification of genes related to Parkinson's disease using expressed sequence tags. |journal=DNA Res. |volume=13 |issue= 6 |pages= 275–86 |year= 2007 |pmid= 17213182 |doi= 10.1093/dnares/dsl016

External links

*

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