FGF6

FGF6

Fibroblast growth factor 6, also known as FGF6, is a human gene.cite web | title = Entrez Gene: FGF6 fibroblast growth factor 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2251| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.cite web | title = Entrez Gene: FGF6 fibroblast growth factor 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2251| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Vainikka S, Partanen J, Bellosta P, "et al." |title=Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction. |journal=EMBO J. |volume=11 |issue= 12 |pages= 4273–80 |year= 1992 |pmid= 1385111 |doi=
*cite journal | author=Iida S, Yoshida T, Naito K, "et al." |title=Human hst-2 (FGF-6) oncogene: cDNA cloning and characterization. |journal=Oncogene |volume=7 |issue= 2 |pages= 303–9 |year= 1992 |pmid= 1549352 |doi=
*cite journal | author=Coulier F, Batoz M, Marics I, "et al." |title=Putative structure of the FGF6 gene product and role of the signal peptide. |journal=Oncogene |volume=6 |issue= 8 |pages= 1437–44 |year= 1991 |pmid= 1886714 |doi=
*cite journal | author=Marics I, Adelaide J, Raybaud F, "et al." |title=Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. |journal=Oncogene |volume=4 |issue= 3 |pages= 335–40 |year= 1989 |pmid= 2649847 |doi=
*cite journal | author=Aerssens J, Chaffanet M, Baens M, "et al." |title=Regional assignment of seven loci to 12p13.2-pter by PCR analysis of somatic cell hybrids containing the der(12) or the der(X) chromosome from a mesothelioma showing t(X;12)(q22;p13). |journal=Genomics |volume=20 |issue= 1 |pages= 119–21 |year= 1994 |pmid= 8020938 |doi=
*cite journal | author=Ornitz DM, Xu J, Colvin JS, "et al." |title=Receptor specificity of the fibroblast growth factor family. |journal=J. Biol. Chem. |volume=271 |issue= 25 |pages= 15292–7 |year= 1996 |pmid= 8663044 |doi=
*cite journal | author=Ropiquet F, Giri D, Kwabi-Addo B, "et al." |title=Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. |journal=Cancer Res. |volume=60 |issue= 15 |pages= 4245–50 |year= 2000 |pmid= 10945637 |doi=
*cite journal | author=Duplan SM, Théorêt Y, Kenigsberg RL |title=Antitumor activity of fibroblast growth factors (FGFs) for medulloblastoma may correlate with FGF receptor expression and tumor variant. |journal=Clin. Cancer Res. |volume=8 |issue= 1 |pages= 246–57 |year= 2002 |pmid= 11801566 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Popovici C, Conchonaud F, Birnbaum D, Roubin R |title=Functional phylogeny relates LET-756 to fibroblast growth factor 9. |journal=J. Biol. Chem. |volume=279 |issue= 38 |pages= 40146–52 |year= 2004 |pmid= 15199049 |doi= 10.1074/jbc.M405795200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Platelet-derived growth factor — (PDGF) Identifiers Symbol PDGF Pfam PF00341 InterPro …   Wikipedia

  • Mitogen-activated protein kinase — Identifiers EC number 2.7.11.24 CAS number 142243 02 5 …   Wikipedia

  • Nerve growth factor — (beta polypeptide) Rendering of NGF from PDB 1SG1 …   Wikipedia

  • Extracellular signal-regulated kinases — Main article: Mitogen activated protein kinase In molecular biology, extracellular signal regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions… …   Wikipedia

  • Heparin-binding EGF-like growth factor — PDB rendering based on 1xdt …   Wikipedia

  • PDGFA — Platelet derived growth factor alpha polypeptide Identifiers Symbols PDGFA; PDGF A; PDGF1 External IDs …   Wikipedia

  • PDGFB — Platelet derived growth factor beta polypeptide PDB rendering based on 1pdg …   Wikipedia

  • PDGFC — Platelet derived growth factor C Identifiers Symbols PDGFC; FALLOTEIN; SCDGF External IDs …   Wikipedia

  • PDGFD — Platelet derived growth factor D Identifiers Symbols PDGFD; IEGF; MGC26867; SCDGF B; SCDGFB External IDs …   Wikipedia

  • C12orf5 — Chromosome 12 open reading frame 5, also known as C12orf5, is a human gene. PBB Summary section title = summary text = This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”