- FGF6
Fibroblast growth factor 6, also known as FGF6, is a human
gene .cite web | title = Entrez Gene: FGF6 fibroblast growth factor 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2251| accessdate = ]PBB_Summary
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summary_text = The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.cite web | title = Entrez Gene: FGF6 fibroblast growth factor 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2251| accessdate = ]References
Further reading
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citations =
*cite journal | author=Vainikka S, Partanen J, Bellosta P, "et al." |title=Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction. |journal=EMBO J. |volume=11 |issue= 12 |pages= 4273–80 |year= 1992 |pmid= 1385111 |doi=
*cite journal | author=Iida S, Yoshida T, Naito K, "et al." |title=Human hst-2 (FGF-6) oncogene: cDNA cloning and characterization. |journal=Oncogene |volume=7 |issue= 2 |pages= 303–9 |year= 1992 |pmid= 1549352 |doi=
*cite journal | author=Coulier F, Batoz M, Marics I, "et al." |title=Putative structure of the FGF6 gene product and role of the signal peptide. |journal=Oncogene |volume=6 |issue= 8 |pages= 1437–44 |year= 1991 |pmid= 1886714 |doi=
*cite journal | author=Marics I, Adelaide J, Raybaud F, "et al." |title=Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. |journal=Oncogene |volume=4 |issue= 3 |pages= 335–40 |year= 1989 |pmid= 2649847 |doi=
*cite journal | author=Aerssens J, Chaffanet M, Baens M, "et al." |title=Regional assignment of seven loci to 12p13.2-pter by PCR analysis of somatic cell hybrids containing the der(12) or the der(X) chromosome from a mesothelioma showing t(X;12)(q22;p13). |journal=Genomics |volume=20 |issue= 1 |pages= 119–21 |year= 1994 |pmid= 8020938 |doi=
*cite journal | author=Ornitz DM, Xu J, Colvin JS, "et al." |title=Receptor specificity of the fibroblast growth factor family. |journal=J. Biol. Chem. |volume=271 |issue= 25 |pages= 15292–7 |year= 1996 |pmid= 8663044 |doi=
*cite journal | author=Ropiquet F, Giri D, Kwabi-Addo B, "et al." |title=Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. |journal=Cancer Res. |volume=60 |issue= 15 |pages= 4245–50 |year= 2000 |pmid= 10945637 |doi=
*cite journal | author=Duplan SM, Théorêt Y, Kenigsberg RL |title=Antitumor activity of fibroblast growth factors (FGFs) for medulloblastoma may correlate with FGF receptor expression and tumor variant. |journal=Clin. Cancer Res. |volume=8 |issue= 1 |pages= 246–57 |year= 2002 |pmid= 11801566 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Popovici C, Conchonaud F, Birnbaum D, Roubin R |title=Functional phylogeny relates LET-756 to fibroblast growth factor 9. |journal=J. Biol. Chem. |volume=279 |issue= 38 |pages= 40146–52 |year= 2004 |pmid= 15199049 |doi= 10.1074/jbc.M405795200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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