CPA3

Carboxypeptidase A3 (mast cell), also known as CPA3, is a human gene.cite web | title = Entrez Gene: CPA3 carboxypeptidase A3 (mast cell)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1359| accessdate = ]

PBB_Summary
section_title =
summary_text = Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A3 form, is obtained as a binary complex of a procarboxypeptidase A with a proproteinase E. Mast cell carboxypeptidase A is a secretory granule metalloexopeptidase that has a pH optimum in the neutral to basic range. It resembles pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues.cite web | title = Entrez Gene: CPA3 carboxypeptidase A3 (mast cell)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1359| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Natsuaki M, Stewart CB, Vanderslice P, "et al." |title=Human skin mast cell carboxypeptidase: functional characterization, cDNA cloning, and genealogy. |journal=J. Invest. Dermatol. |volume=99 |issue= 2 |pages= 138–45 |year= 1992 |pmid= 1629626 |doi=
*cite journal | author=Reynolds DS, Gurley DS, Austen KF |title=Cloning and characterization of the novel gene for mast cell carboxypeptidase A. |journal=J. Clin. Invest. |volume=89 |issue= 1 |pages= 273–82 |year= 1992 |pmid= 1729276 |doi=
*cite journal | author=Goldstein SM, Kaempfer CE, Proud D, "et al." |title=Detection and partial characterization of a human mast cell carboxypeptidase. |journal=J. Immunol. |volume=139 |issue= 8 |pages= 2724–9 |year= 1987 |pmid= 2443571 |doi=
*cite journal | author=Reynolds DS, Gurley DS, Stevens RL, "et al." |title=Cloning of cDNAs that encode human mast cell carboxypeptidase A, and comparison of the protein with mouse mast cell carboxypeptidase A and rat pancreatic carboxypeptidases. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 23 |pages= 9480–4 |year= 1990 |pmid= 2594780 |doi=
*cite journal | author=Goldstein SM, Kaempfer CE, Kealey JT, Wintroub BU |title=Human mast cell carboxypeptidase. Purification and characterization. |journal=J. Clin. Invest. |volume=83 |issue= 5 |pages= 1630–6 |year= 1989 |pmid= 2708524 |doi=
*cite journal | author=Pascual R, Burgos FJ, Salva M, "et al." |title=Purification and properties of five different forms of human procarboxypeptidases. |journal=Eur. J. Biochem. |volume=179 |issue= 3 |pages= 609–16 |year= 1989 |pmid= 2920728 |doi=
*cite journal | author=Dikov MM, Springman EB, Yeola S, Serafin WE |title=Processing of procarboxypeptidase A and other zymogens in murine mast cells. |journal=J. Biol. Chem. |volume=269 |issue= 41 |pages= 25897–904 |year= 1994 |pmid= 7929294 |doi=
*cite journal | author=Huang H, Reed CP, Zhang JS, "et al." |title=Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. |journal=Cancer Res. |volume=59 |issue= 12 |pages= 2981–8 |year= 1999 |pmid= 10383164 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chen ZQ, He SH |title=Cloning and expression of human colon mast cell carboxypeptidase. |journal=World J. Gastroenterol. |volume=10 |issue= 3 |pages= 342–7 |year= 2004 |pmid= 14760754 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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