EDF1

Endothelial differentiation-related factor 1, also known as EDF1, is a human gene.cite web | title = Entrez Gene: EDF1 endothelial differentiation-related factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8721| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.cite web | title = Entrez Gene: EDF1 endothelial differentiation-related factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8721| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Li FQ, Ueda H, Hirose S |title=Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1. |journal=Mol. Cell. Biol. |volume=14 |issue= 5 |pages= 3013–21 |year= 1994 |pmid= 8164657 |doi=
*cite journal | author=Dragoni I, Mariotti M, Consalez GG, "et al." |title=EDF-1, a novel gene product down-regulated in human endothelial cell differentiation. |journal=J. Biol. Chem. |volume=273 |issue= 47 |pages= 31119–24 |year= 1998 |pmid= 9813014 |doi=
*cite journal | author=Ozaki J, Takemaru KI, Ikegami T, "et al." |title=Identification of the core domain and the secondary structure of the transcriptional coactivator MBF1. |journal=Genes Cells |volume=4 |issue= 7 |pages= 415–24 |year= 1999 |pmid= 10469174 |doi=
*cite journal | author=Kabe Y, Goto M, Shima D, "et al." |title=The role of human MBF1 as a transcriptional coactivator. |journal=J. Biol. Chem. |volume=274 |issue= 48 |pages= 34196–202 |year= 1999 |pmid= 10567391 |doi=
*cite journal | author=Mariotti M, De Benedictis L, Avon E, Maier JA |title=Interaction between endothelial differentiation-related factor-1 and calmodulin in vitro and in vivo. |journal=J. Biol. Chem. |volume=275 |issue= 31 |pages= 24047–51 |year= 2000 |pmid= 10816571 |doi= 10.1074/jbc.M001928200
*cite journal | author=Brendel C, Gelman L, Auwerx J |title=Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism. |journal=Mol. Endocrinol. |volume=16 |issue= 6 |pages= 1367–77 |year= 2003 |pmid= 12040021 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ballabio E, Mariotti M, De Benedictis L, Maier JA |title=The dual role of endothelial differentiation-related factor-1 in the cytosol and nucleus: modulation by protein kinase A. |journal=Cell. Mol. Life Sci. |volume=61 |issue= 9 |pages= 1069–74 |year= 2004 |pmid= 15112053 |doi= 10.1007/s00018-004-4016-0
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Bolognese F, Pitarque-Martì M, Lo Cicero V, "et al." |title=Characterization of the human EDF-1 minimal promoter: involvement of NFY and Sp1 in the regulation of basal transcription. |journal=Gene |volume=374 |issue= |pages= 87–95 |year= 2006 |pmid= 16567061 |doi= 10.1016/j.gene.2006.01.030

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