ALOX12B

Arachidonate 12-lipoxygenase, 12R type, also known as ALOX12B, is a human gene.cite web | title = Entrez Gene: ALOX12B arachidonate 12-lipoxygenase, 12R type| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=242| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes an enzyme involved in the conversion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.cite web | title = Entrez Gene: ALOX12B arachidonate 12-lipoxygenase, 12R type| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=242| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yu Z, Schneider C, Boeglin WE, Brash AR |title=Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha. |journal=Lipids |volume=42 |issue= 6 |pages= 491–7 |year= 2007 |pmid= 17436029 |doi= 10.1007/s11745-007-3054-4
*cite journal | author=Lesueur F, Bouadjar B, Lefèvre C, "et al." |title=Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13. |journal=J. Invest. Dermatol. |volume=127 |issue= 4 |pages= 829–34 |year= 2007 |pmid= 17139268 |doi= 10.1038/sj.jid.5700640
*cite journal | author=Yu Z, Schneider C, Boeglin WE, Brash AR |title=Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3. |journal=Biochim. Biophys. Acta |volume=1686 3 |issue= |pages= 238–47 |year= 2005 |pmid= 15629692 |doi= 10.1016/j.bbalip.2004.10.007
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=McDonnell M, Li H, Funk CD |title=Characterization of epidermal 12(S) and 12(R) lipoxygenases. |journal=Adv. Exp. Med. Biol. |volume=507 |issue= |pages= 147–53 |year= 2003 |pmid= 12664578 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jobard F, Lefèvre C, Karaduman A, "et al." |title=Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1. |journal=Hum. Mol. Genet. |volume=11 |issue= 1 |pages= 107–13 |year= 2002 |pmid= 11773004 |doi=
*cite journal | author=Schneider C, Keeney DS, Boeglin WE, Brash AR |title=Detection and cellular localization of 12R-lipoxygenase in human tonsils. |journal=Arch. Biochem. Biophys. |volume=386 |issue= 2 |pages= 268–74 |year= 2001 |pmid= 11368351 |doi= 10.1006/abbi.2000.2217
*cite journal | author=Krieg P, Marks F, Fürstenberger G |title=A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression. |journal=Genomics |volume=73 |issue= 3 |pages= 323–30 |year= 2001 |pmid= 11350124 |doi= 10.1006/geno.2001.6519
*cite journal | author=Tang K, Finley RL, Nie D, Honn KV |title=Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening. |journal=Biochemistry |volume=39 |issue= 12 |pages= 3185–91 |year= 2000 |pmid= 10727209 |doi=
*cite journal | author=Sun D, McDonnell M, Chen XS, "et al." |title=Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment. |journal=J. Biol. Chem. |volume=273 |issue= 50 |pages= 33540–7 |year= 1999 |pmid= 9837935 |doi=
*cite journal | author=Boeglin WE, Kim RB, Brash AR |title=A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 12 |pages= 6744–9 |year= 1998 |pmid= 9618483 |doi=

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