USP15

Ubiquitin specific peptidase 15, also known as USP15, is a human gene.cite web | title = Entrez Gene: USP15 ubiquitin specific peptidase 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9958| accessdate = ]

PBB_Summary
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summary_text = Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478). [supplied by OMIM] cite web | title = Entrez Gene: USP15 ubiquitin specific peptidase 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9958| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Puente XS, Sánchez LM, Overall CM, López-Otín C |title=Human and mouse proteases: a comparative genomic approach. |journal=Nat. Rev. Genet. |volume=4 |issue= 7 |pages= 544–58 |year= 2003 |pmid= 12838346 |doi= 10.1038/nrg1111
*cite journal | author=Nakajima D, Okazaki N, Yamakawa H, "et al." |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=
*cite journal | author=D'Andrea A, Pellman D |title=Deubiquitinating enzymes: a new class of biological regulators. |journal=Crit. Rev. Biochem. Mol. Biol. |volume=33 |issue= 5 |pages= 337–52 |year= 1999 |pmid= 9827704 |doi=
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=de Jong RN, Ab E, Diercks T, "et al." |title=Solution structure of the human ubiquitin-specific protease 15 DUSP domain. |journal=J. Biol. Chem. |volume=281 |issue= 8 |pages= 5026–31 |year= 2006 |pmid= 16298993 |doi= 10.1074/jbc.M510993200
*cite journal | author=Hetfeld BK, Helfrich A, Kapelari B, "et al." |title=The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1. |journal=Curr. Biol. |volume=15 |issue= 13 |pages= 1217–21 |year= 2005 |pmid= 16005295 |doi= 10.1016/j.cub.2005.05.059
*cite journal | author=Soboleva TA, Jans DA, Johnson-Saliba M, Baker RT |title=Nuclear-cytoplasmic shuttling of the oncogenic mouse UNP/USP4 deubiquitylating enzyme. |journal=J. Biol. Chem. |volume=280 |issue= 1 |pages= 745–52 |year= 2005 |pmid= 15494318 |doi= 10.1074/jbc.M401394200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Angelats C, Wang XW, Jermiin LS, "et al." |title=Isolation and characterization of the mouse ubiquitin-specific protease Usp15. |journal=Mamm. Genome |volume=14 |issue= 1 |pages= 31–46 |year= 2003 |pmid= 12532266 |doi= 10.1007/s00335-002-3035-0
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Baker RT, Wang XW, Woollatt E, "et al." |title=Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases. |journal=Genomics |volume=59 |issue= 3 |pages= 264–74 |year= 1999 |pmid= 10444327 |doi= 10.1006/geno.1999.5879
*cite journal | author=Nagase T, Ishikawa K, Miyajima N, "et al." |title=Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 1 |pages= 31–9 |year= 1998 |pmid= 9628581 |doi=

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