USP11

Ubiquitin specific peptidase 11, also known as USP11, is a human gene.cite web | title = Entrez Gene: USP11 ubiquitin specific peptidase 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8237| accessdate = ]

PBB_Summary
section_title =
summary_text = Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23cite web | title = Entrez Gene: USP11 ubiquitin specific peptidase 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8237| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=D'Andrea A, Pellman D |title=Deubiquitinating enzymes: a new class of biological regulators. |journal=Crit. Rev. Biochem. Mol. Biol. |volume=33 |issue= 5 |pages= 337–52 |year= 1999 |pmid= 9827704 |doi=
*cite journal | author=Puente XS, Sánchez LM, Overall CM, López-Otín C |title=Human and mouse proteases: a comparative genomic approach. |journal=Nat. Rev. Genet. |volume=4 |issue= 7 |pages= 544–58 |year= 2003 |pmid= 12838346 |doi= 10.1038/nrg1111
*cite journal | author=Swanson DA, Freund CL, Ploder L, "et al." |title=A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders. |journal=Hum. Mol. Genet. |volume=5 |issue= 4 |pages= 533–8 |year= 1996 |pmid= 8845848 |doi=
*cite journal | author=Brandau O, Nyakatura G, Jedele KB, "et al." |title=UHX1 and PCTK1: precise characterisation and localisation within a gene-rich region in Xp11.23 and evaluation as candidate genes for retinal diseases mapped to Xp21.1-p11.2. |journal=Eur. J. Hum. Genet. |volume=6 |issue= 5 |pages= 459–66 |year= 1999 |pmid= 9801870 |doi= 10.1038/sj.ejhg.5200207
*cite journal | author=Stoddart KL, Jermak C, Nagaraja R, "et al." |title=Physical map covering a 2 Mb region in human xp11.3 distal to DX6849. |journal=Gene |volume=227 |issue= 1 |pages= 111–6 |year= 1999 |pmid= 9931462 |doi=
*cite journal | author=Thiselton DL, McDowall J, Brandau O, "et al." |title=An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders. |journal=Genomics |volume=79 |issue= 4 |pages= 560–72 |year= 2002 |pmid= 11944989 |doi= 10.1006/geno.2002.6733
*cite journal | author=Ideguchi H, Ueda A, Tanaka M, "et al." |title=Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM. |journal=Biochem. J. |volume=367 |issue= Pt 1 |pages= 87–95 |year= 2003 |pmid= 12084015 |doi= 10.1042/BJ20011851
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Angelats C, Wang XW, Jermiin LS, "et al." |title=Isolation and characterization of the mouse ubiquitin-specific protease Usp15. |journal=Mamm. Genome |volume=14 |issue= 1 |pages= 31–46 |year= 2003 |pmid= 12532266 |doi= 10.1007/s00335-002-3035-0
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Schoenfeld AR, Apgar S, Dolios G, "et al." |title=BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage. |journal=Mol. Cell. Biol. |volume=24 |issue= 17 |pages= 7444–55 |year= 2004 |pmid= 15314155 |doi= 10.1128/MCB.24.17.7444-7455.2004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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