Yuremamine

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OtherNames=Yuremamine
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SMILES=Oc4c(O)cc(cc4O)C(C1O)n2c5ccccc5c(CCN(C)C)c2C1c3ccc(O)cc3O
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Formula=C₂₇H₂₈N₂O₆
MolarMass=476.520
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Yuremamine is a phytoindole alkaloid which was first isolated and identified from the plant material of "Mimosa tenuiflora" in 2005. It may explain the reason that the dimethyltryptamine in some ayahuasca preparations is orally active without the presence of any known MAOI. [Vepsäläinen, J. J.; Auriola, S.; Tukiainen, M.; Ropponen, N. & Callaway, J. (2005). "Isolation and characterization of Yuremamine, a new phytoindole". "Planta Medica" 71(11): 1049-1053.]

As a pure compound, yuremamine is a dark red-purple amorphous solid. It represents a new family of indole derivatives, and interestingly the indole ring in this compound contains the same N,N-dimethyl moiety that is seen in N,N-dimethyltryptamine. The specific reason it has been thought to be an MAOI is due to the intra-molecular hydrogen bonding of this tertiary amine.

There has been speculation that yuremamine is identical with the dark red "jungle spice" that has been commonly isolated from extractions of Mimosa hostilis, sometimes as a contaminant and sometimes deliberately as a separate fraction. In addition to matching a similar physical description, there is substantial anecdotal evidence that this "jungle spice" is pharmacologically active in humans and acts in a manner qualitatively similar to a tryptamine. [ [http://www.dmt-nexus.com/phpBB2/viewtopic.php?t=75&postdays=0&postorder=asc&start= :: View topic - Dark DMT - the Other Alkaloid ] ] There is no direct evidence that this compound has been isolated by home extractors, and in fact virtually all evidence points away from this possibility. [ [http://www.dmt-nexus.com/forum/Default.aspx?g=posts&t=1115 "Jungle Spice" - Mystery Alkaloids of Mimosa Root Bark - Information - Welcome to the DMT-Nexus ] ]

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