UCHL3

UCHL3

Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase), also known as UCHL3, is a human gene.cite web | title = Entrez Gene: UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7347| accessdate = ]

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ee also

* Ubiquitin carboxy-terminal hydrolase L1 -- an enzyme

References

Further reading

PBB_Further_reading
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*cite journal | author=Wilkinson KD, Lee KM, Deshpande S, "et al." |title=The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase. |journal=Science |volume=246 |issue= 4930 |pages= 670–3 |year= 1989 |pmid= 2530630 |doi=
*cite journal | author=Johnston SC, Larsen CN, Cook WJ, "et al." |title=Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution. |journal=EMBO J. |volume=16 |issue= 13 |pages= 3787–96 |year= 1997 |pmid= 9233788 |doi= 10.1093/emboj/16.13.3787
*cite journal | author=Wada H, Kito K, Caskey LS, "et al." |title=Cleavage of the C-terminus of NEDD8 by UCH-L3. |journal=Biochem. Biophys. Res. Commun. |volume=251 |issue= 3 |pages= 688–92 |year= 1998 |pmid= 9790970 |doi= 10.1006/bbrc.1998.9532
*cite journal | author=Wilkinson KD, Laleli-Sahin E, Urbauer J, "et al." |title=The binding site for UCH-L3 on ubiquitin: mutagenesis and NMR studies on the complex between ubiquitin and UCH-L3. |journal=J. Mol. Biol. |volume=291 |issue= 5 |pages= 1067–77 |year= 1999 |pmid= 10518943 |doi=
*cite journal | author=Baek SH, Yoo YJ, Tanaka K, Chung CH |title=Molecular cloning of chick UCH-6 which shares high similarity with human UCH-L3: its unusual substrate specificity and tissue distribution. |journal=Biochem. Biophys. Res. Commun. |volume=264 |issue= 1 |pages= 235–40 |year= 1999 |pmid= 10527871 |doi= 10.1006/bbrc.1999.1492
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Saito S, Iida A, Sekine A, "et al." |title=Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population. |journal=J. Hum. Genet. |volume=48 |issue= 5 |pages= 249–70 |year= 2003 |pmid= 12721789 |doi= 10.1007/s10038-003-0021-7
*cite journal | author=Nam MJ, Madoz-Gurpide J, Wang H, "et al." |title=Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3. |journal=Proteomics |volume=3 |issue= 11 |pages= 2108–15 |year= 2004 |pmid= 14595809 |doi= 10.1002/pmic.200300594
*cite journal | author=Dunham A, Matthews LH, Burton J, "et al." |title=The DNA sequence and analysis of human chromosome 13. |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Misaghi S, Galardy PJ, Meester WJ, "et al." |title=Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate. |journal=J. Biol. Chem. |volume=280 |issue= 2 |pages= 1512–20 |year= 2005 |pmid= 15531586 |doi= 10.1074/jbc.M410770200
*cite journal | author=Rolén U, Kobzeva V, Gasparjan N, "et al." |title=Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines. |journal=Mol. Carcinog. |volume=45 |issue= 4 |pages= 260–9 |year= 2006 |pmid= 16402389 |doi= 10.1002/mc.20177
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032

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  • Ubiquitin carboxy-terminal hydrolase L1 — (UCH L1) (EC number|3.1.2.15) is a deubiqutinating enzyme. PBB Summary section title = summary text = UCHL1 is a member of a gene family whose products hydrolyze small C terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression… …   Wikipedia

  • NEDD8 — Neural precursor cell expressed, developmentally down regulated 8 PDB rendering based on 1ndd …   Wikipedia

  • Deubiquitinating enzyme — Deubiquitinating enzymes (DUBs) are a large group of proteases[1] (more than 60 known) that regulate ubiquitin dependent metabolic pathways by cleaving ubiquitin protein bonds. DUBs are also commonly referred to as deubiquitinating peptidases,… …   Wikipedia

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