- EPN2
Epsin 2, also known as EPN2, is a human
gene .cite web | title = Entrez Gene: EPN2 epsin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22905| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in two transcript variants encoding different isoforms.cite web | title = Entrez Gene: EPN2 epsin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22905| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Salcini AE, Confalonieri S, Doria M, "et al." |title=Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. |journal=Genes Dev. |volume=11 |issue= 17 |pages= 2239–49 |year= 1997 |pmid= 9303539 |doi=
*cite journal | author=Yamabhai M, Hoffman NG, Hardison NL, "et al." |title=Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains. |journal=J. Biol. Chem. |volume=273 |issue= 47 |pages= 31401–7 |year= 1998 |pmid= 9813051 |doi=
*cite journal | author=Kikuno R, Nagase T, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=
*cite journal | author=Rosenthal JA, Chen H, Slepnev VI, "et al." |title=The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module. |journal=J. Biol. Chem. |volume=274 |issue= 48 |pages= 33959–65 |year= 1999 |pmid= 10567358 |doi=
*cite journal | author=Ford MG, Mills IG, Peter BJ, "et al." |title=Curvature of clathrin-coated pits driven by epsin. |journal=Nature |volume=419 |issue= 6905 |pages= 361–6 |year= 2002 |pmid= 12353027 |doi= 10.1038/nature01020
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hussain NK, Yamabhai M, Bhakar AL, "et al." |title=A role for epsin N-terminal homology/AP180 N-terminal homology (ENTH/ANTH) domains in tubulin binding. |journal=J. Biol. Chem. |volume=278 |issue= 31 |pages= 28823–30 |year= 2003 |pmid= 12750376 |doi= 10.1074/jbc.M300995200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051
*cite journal | author=Ballif BA, Villén J, Beausoleil SA, "et al." |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell Proteomics |volume=3 |issue= 11 |pages= 1093–101 |year= 2005 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026PBB_Controls
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