CPSF6

Cleavage and polyadenylation specific factor 6, 68kDa, also known as CPSF6, is a human gene.cite web | title = Entrez Gene: CPSF6 cleavage and polyadenylation specific factor 6, 68kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11052| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.cite web | title = Entrez Gene: CPSF6 cleavage and polyadenylation specific factor 6, 68kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11052| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Rüegsegger U, Beyer K, Keller W |title=Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors. |journal=J. Biol. Chem. |volume=271 |issue= 11 |pages= 6107–13 |year= 1996 |pmid= 8626397 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Rüegsegger U, Blank D, Keller W |title=Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits. |journal=Mol. Cell |volume=1 |issue= 2 |pages= 243–53 |year= 1998 |pmid= 9659921 |doi=
*cite journal | author=de Vries H, Rüegsegger U, Hübner W, "et al." |title=Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. |journal=EMBO J. |volume=19 |issue= 21 |pages= 5895–904 |year= 2000 |pmid= 11060040 |doi= 10.1093/emboj/19.21.5895
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Awasthi S, Alwine JC |title=Association of polyadenylation cleavage factor I with U1 snRNP. |journal=RNA |volume=9 |issue= 11 |pages= 1400–9 |year= 2003 |pmid= 14561889 |doi=
*cite journal | author=Brown KM, Gilmartin GM |title=A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im. |journal=Mol. Cell |volume=12 |issue= 6 |pages= 1467–76 |year= 2004 |pmid= 14690600 |doi=
*cite journal | author=Dettwiler S, Aringhieri C, Cardinale S, "et al." |title=Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. |journal=J. Biol. Chem. |volume=279 |issue= 34 |pages= 35788–97 |year= 2005 |pmid= 15169763 |doi= 10.1074/jbc.M403927200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Venkataraman K, Brown KM, Gilmartin GM |title=Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition. |journal=Genes Dev. |volume=19 |issue= 11 |pages= 1315–27 |year= 2005 |pmid= 15937220 |doi= 10.1101/gad.1298605
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Millevoi S, Loulergue C, Dettwiler S, "et al." |title=An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries. |journal=EMBO J. |volume=25 |issue= 20 |pages= 4854–64 |year= 2006 |pmid= 17024186 |doi= 10.1038/sj.emboj.7601331
*cite journal | author=Cardinale S, Cisterna B, Bonetti P, "et al." |title=Subnuclear localization and dynamics of the Pre-mRNA 3' end processing factor mammalian cleavage factor I 68-kDa subunit. |journal=Mol. Biol. Cell |volume=18 |issue= 4 |pages= 1282–92 |year= 2007 |pmid= 17267687 |doi= 10.1091/mbc.E06-09-0846
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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