VAMP4

VAMP4

Vesicle-associated membrane protein 4, also known as VAMP4, is a human gene.cite web | title = Entrez Gene: VAMP4 vesicle-associated membrane protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8674| accessdate = ]

PBB_Summary
section_title =
summary_text = Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.cite web | title = Entrez Gene: VAMP4 vesicle-associated membrane protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8674| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Advani RJ, Bae HR, Bock JB, "et al." |title=Seven novel mammalian SNARE proteins localize to distinct membrane compartments. |journal=J. Biol. Chem. |volume=273 |issue= 17 |pages= 10317–24 |year= 1998 |pmid= 9553086 |doi=
*cite journal | author=Steegmaier M, Klumperman J, Foletti DL, "et al." |title=Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking. |journal=Mol. Biol. Cell |volume=10 |issue= 6 |pages= 1957–72 |year= 1999 |pmid= 10359608 |doi=
*cite journal | author=Scales SJ, Chen YA, Yoo BY, "et al." |title=SNAREs contribute to the specificity of membrane fusion. |journal=Neuron |volume=26 |issue= 2 |pages= 457–64 |year= 2000 |pmid= 10839363 |doi=
*cite journal | author=Peden AA, Park GY, Scheller RH |title=The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding. |journal=J. Biol. Chem. |volume=276 |issue= 52 |pages= 49183–7 |year= 2002 |pmid= 11598115 |doi= 10.1074/jbc.M106646200
*cite journal | author=Mallard F, Tang BL, Galli T, "et al." |title=Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. |journal=J. Cell Biol. |volume=156 |issue= 4 |pages= 653–64 |year= 2002 |pmid= 11839770 |doi= 10.1083/jcb.200110081
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zeng Q, Tran TT, Tan HX, Hong W |title=The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network. |journal=J. Biol. Chem. |volume=278 |issue= 25 |pages= 23046–54 |year= 2003 |pmid= 12682051 |doi= 10.1074/jbc.M303214200
*cite journal | author=Hinners I, Wendler F, Fei H, "et al." |title=AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1. |journal=EMBO Rep. |volume=4 |issue= 12 |pages= 1182–9 |year= 2004 |pmid= 14608369 |doi= 10.1038/sj.embor.7400018
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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  • Vesicle-associated membrane protein — (VAMP) family of proteins includes proteins with similar structure. * VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neuromediator release. * VAMP3… …   Wikipedia

  • PACS1 — Phosphofurin acidic cluster sorting protein 1 Identifiers Symbols PACS1; FLJ10209; KIAA1175 External IDs …   Wikipedia

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