PLA2G2D

PLA2G2D

Phospholipase A2, group IID, also known as PLA2G2D, is a human gene.cite web | title = Entrez Gene: PLA2G2D phospholipase A2, group IID| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26279| accessdate = ]

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References

Further reading

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*cite journal | author=Schröder HC, Perovic S, Kavsan V, "et al." |title=Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death. |journal=Neurotoxicology |volume=19 |issue= 4-5 |pages= 683–8 |year= 1998 |pmid= 9745929 |doi=
*cite journal | author=Leslie CC |title=Regulation of arachidonic acid availability for eicosanoid production. |journal=Biochem. Cell Biol. |volume=82 |issue= 1 |pages= 1–17 |year= 2004 |pmid= 15052324 |doi= 10.1139/o03-080
*cite journal | author=Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V, "et al." |title=HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=16 |issue= 1 |pages= 1–9 |year= 1997 |pmid= 9377118 |doi=
*cite journal | author=Ishizaki J, Suzuki N, Higashino K, "et al." |title=Cloning and characterization of novel mouse and human secretory phospholipase A(2)s. |journal=J. Biol. Chem. |volume=274 |issue= 35 |pages= 24973–9 |year= 1999 |pmid= 10455175 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Shakhov AN, Rubtsov AV, Lyakhov IG, "et al." |title=SPLASH (PLA2IID), a novel member of phospholipase A2 family, is associated with lymphotoxin deficiency. |journal=Genes Immun. |volume=1 |issue= 3 |pages= 191–9 |year= 2001 |pmid= 11196711 |doi= 10.1038/sj.gene.6363659
*cite journal | author=Lindbom J, Ljungman AG, Lindahl M, Tagesson C |title=Increased gene expression of novel cytosolic and secretory phospholipase A(2) types in human airway epithelial cells induced by tumor necrosis factor-alpha and IFN-gamma. |journal=J. Interferon Cytokine Res. |volume=22 |issue= 9 |pages= 947–55 |year= 2003 |pmid= 12396716 |doi= 10.1089/10799900260286650
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Eckey R, Menschikowski M, Lattke P, Jaross W |title=Increased hepatic cholesterol accumulation in transgenic mice overexpressing human secretory phospholipase A2 group IIA. |journal=Inflammation |volume=28 |issue= 2 |pages= 59–65 |year= 2005 |pmid= 15379211 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Takabatake N, Sata M, Inoue S, "et al." |title=A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease. |journal=Am. J. Respir. Crit. Care Med. |volume=172 |issue= 9 |pages= 1097–104 |year= 2006 |pmid= 16002569 |doi= 10.1164/rccm.200503-319OC
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Lindbom J, Ljungman AG, Tagesson C |title=Interferon gamma-induced gene expression of the novel secretory phospholipase A2 type IID in human monocyte-derived macrophages is inhibited by lipopolysaccharide. |journal=Inflammation |volume=29 |issue= 2-3 |pages= 108–117 |year= 2007 |pmid= 16897354 |doi= 10.1007/s10753-006-9007-x

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  • Phospholipase A2 — Phospholipases A2 (PLA2s) EC number|3.1.1.4 are upstream regulators of many inflammatory processes. This particular phospholipase specifically recognizes the sn 2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing… …   Wikipedia

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