- TOMM34
Translocase of outer mitochondrial membrane 34, also known as TOMM34, is a human
gene .cite web | title = Entrez Gene: TOMM34 translocase of outer mitochondrial membrane 34| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10953| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats.cite web | title = Entrez Gene: TOMM34 translocase of outer mitochondrial membrane 34| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10953| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Nuttall SD, Hanson BJ, Mori M, Hoogenraad NJ |title=hTom34: a novel translocase for the import of proteins into human mitochondria. |journal=DNA Cell Biol. |volume=16 |issue= 9 |pages= 1067–74 |year= 1997 |pmid= 9324309 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Young JC, Obermann WM, Hartl FU |title=Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90. |journal=J. Biol. Chem. |volume=273 |issue= 29 |pages= 18007–10 |year= 1998 |pmid= 9660753 |doi=
*cite journal | author=Chewawiwat N, Yano M, Terada K, "et al." |title=Characterization of the novel mitochondrial protein import component, Tom34, in mammalian cells. |journal=J. Biochem. |volume=125 |issue= 4 |pages= 721–7 |year= 1999 |pmid= 10101285 |doi=
*cite journal | author=Fossey SC, Mychaleckyj JC, Pendleton JK, "et al." |title=A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20. |journal=Genomics |volume=76 |issue= 1-3 |pages= 45–57 |year= 2001 |pmid= 11549316 |doi= 10.1006/geno.2001.6584
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Mukhopadhyay A, Avramova LV, Weiner H |title=Tom34 unlike Tom20 does not interact with the leader sequences of mitochondrial precursor proteins. |journal=Arch. Biochem. Biophys. |volume=400 |issue= 1 |pages= 97–104 |year= 2002 |pmid= 11913975 |doi= 10.1006/abbi.2002.2777
*cite journal | author=Yang CS, Weiner H |title=Yeast two-hybrid screening identifies binding partners of human Tom34 that have ATPase activity and form a complex with Tom34 in the cytosol. |journal=Arch. Biochem. Biophys. |volume=400 |issue= 1 |pages= 105–10 |year= 2002 |pmid= 11913976 |doi= 10.1006/abbi.2002.2778
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Shimokawa T, Matsushima S, Tsunoda T, "et al." |title=Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target. |journal=Int. J. Oncol. |volume=29 |issue= 2 |pages= 381–6 |year= 2006 |pmid= 16820880 |doi=
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.