- RGS20
Regulator of G-protein signalling 20, also known as RGS20, is a human
gene .cite web | title = Entrez Gene: RGS20 regulator of G-protein signalling 20| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8601| accessdate = ]PBB_Summary
section_title =
summary_text = Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. [supplied by OMIM] cite web | title = Entrez Gene: RGS20 regulator of G-protein signalling 20| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8601| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Glick JL, Meigs TE, Miron A, Casey PJ |title=RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 26008–13 |year= 1998 |pmid= 9748279 |doi=
*cite journal | author=Wang J, Ducret A, Tu Y, "et al." |title=RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 26014–25 |year= 1998 |pmid= 9748280 |doi=
*cite journal | author=Barker SA, Wang J, Sierra DA, Ross EM |title=RGSZ1 and Ret RGS: two of several splice variants from the gene RGS20. |journal=Genomics |volume=78 |issue= 3 |pages= 223–9 |year= 2002 |pmid= 11735229 |doi= 10.1006/geno.2001.6659
*cite journal | author=Sierra DA, Gilbert DJ, Householder D, "et al." |title=Evolution of the regulators of G-protein signaling multigene family in mouse and human. |journal=Genomics |volume=79 |issue= 2 |pages= 177–85 |year= 2002 |pmid= 11829488 |doi= 10.1006/geno.2002.6693
*cite journal | author=Nixon AB, Grenningloh G, Casey PJ |title=The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly. |journal=J. Biol. Chem. |volume=277 |issue= 20 |pages= 18127–33 |year= 2002 |pmid= 11882662 |doi= 10.1074/jbc.M201065200
*cite journal | author=Wang Y, Ho G, Zhang JJ, "et al." |title=Regulator of G protein signaling Z1 (RGSZ1) interacts with Galpha i subunits and regulates Galpha i-mediated cell signaling. |journal=J. Biol. Chem. |volume=277 |issue= 50 |pages= 48325–32 |year= 2003 |pmid= 12379657 |doi= 10.1074/jbc.M206116200
*cite journal | author=Nagahama M, Usui S, Shinohara T, "et al." |title=Inactivation of Galpha(z) causes disassembly of the Golgi apparatus. |journal=J. Cell. Sci. |volume=115 |issue= Pt 23 |pages= 4483–93 |year= 2003 |pmid= 12414994 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Fischer T, De Vries L, Meerloo T, Farquhar MG |title=Promotion of G alpha i3 subunit down-regulation by GIPN, a putative E3 ubiquitin ligase that interacts with RGS-GAIP. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 14 |pages= 8270–5 |year= 2003 |pmid= 12826607 |doi= 10.1073/pnas.1432965100
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Xu GY, Hum WT, Sukits SF, "et al." |title=1H, 13C and 15N resonance assignments of human RGSZ1. |journal=J. Biomol. NMR |volume=28 |issue= 4 |pages= 409–10 |year= 2004 |pmid= 14872136 |doi= 10.1023/B:JNMR.0000015374.29659.f9
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Ajit SK, Ramineni S, Edris W, "et al." |title=RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling. |journal=Cell. Signal. |volume=19 |issue= 4 |pages= 723–30 |year= 2007 |pmid= 17126529 |doi= 10.1016/j.cellsig.2006.09.008
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134PBB_Controls
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