CSMD1

CSMD1

CUB and Sushi multiple domains 1, also known as CSMD1, is a human gene.cite web | title = Entrez Gene: CSMD1 CUB and Sushi multiple domains 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64478| accessdate = ] . It is a potential tumour supressor, the deletion of which may result in head and neck carcinomas behaving more aggressively.

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References

Further reading

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*cite journal | author=Smith DI, Zhu Y, McAvoy S, Kuhn R |title=Common fragile sites, extremely large genes, neural development and cancer. |journal=Cancer Lett. |volume=232 |issue= 1 |pages= 48–57 |year= 2006 |pmid= 16221525 |doi= 10.1016/j.canlet.2005.06.049
*cite journal | author=Sun PC, Uppaluri R, Schmidt AP, "et al." |title=Transcript map of the 8p23 putative tumor suppressor region. |journal=Genomics |volume=75 |issue= 1-3 |pages= 17–25 |year= 2001 |pmid= 11472063 |doi= 10.1006/geno.2001.6587
*cite journal | author=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. |journal=DNA Res. |volume=8 |issue= 4 |pages= 179–87 |year= 2002 |pmid= 11572484 |doi=
*cite journal | author=Toomes C, Jackson A, Maguire K, "et al." |title=The presence of multiple regions of homozygous deletion at the CSMD1 locus in oral squamous cell carcinoma question the role of CSMD1 in head and neck carcinogenesis. |journal=Genes Chromosomes Cancer |volume=37 |issue= 2 |pages= 132–40 |year= 2003 |pmid= 12696061 |doi= 10.1002/gcc.10191
*cite journal | author=Henshall SM, Afar DE, Hiller J, "et al." |title=Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse. |journal=Cancer Res. |volume=63 |issue= 14 |pages= 4196–203 |year= 2003 |pmid= 12874026 |doi=
*cite journal | author=Lau WL, Scholnick SB |title=Identification of two new members of the CSMD gene family. |journal=Genomics |volume=82 |issue= 3 |pages= 412–5 |year= 2004 |pmid= 12906867 |doi=
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Scholnick SB, Richter TM |title=The role of CSMD1 in head and neck carcinogenesis. |journal=Genes Chromosomes Cancer |volume=38 |issue= 3 |pages= 281–3 |year= 2003 |pmid= 14506705 |doi= 10.1002/gcc.10279
*cite journal | author=Clark AG, Glanowski S, Nielsen R, "et al." |title=Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. |journal=Science |volume=302 |issue= 5652 |pages= 1960–3 |year= 2003 |pmid= 14671302 |doi= 10.1126/science.1088821
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Paris PL, Andaya A, Fridlyand J, "et al." |title=Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. |journal=Hum. Mol. Genet. |volume=13 |issue= 13 |pages= 1303–13 |year= 2005 |pmid= 15138198 |doi= 10.1093/hmg/ddh155
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Richter TM, Tong BD, Scholnick SB |title=Epigenetic inactivation and aberrant transcription of CSMD1 in squamous cell carcinoma cell lines. |journal=Cancer Cell Int. |volume=5 |issue= |pages= 29 |year= 2005 |pmid= 16153303 |doi= 10.1186/1475-2867-5-29
*cite journal | author=Blaveri E, Brewer JL, Roydasgupta R, "et al." |title=Bladder cancer stage and outcome by array-based comparative genomic hybridization. |journal=Clin. Cancer Res. |volume=11 |issue= 19 Pt 1 |pages= 7012–22 |year= 2006 |pmid= 16203795 |doi= 10.1158/1078-0432.CCR-05-0177
*cite journal | author=Nusbaum C, Mikkelsen TS, Zody MC, "et al." |title=DNA sequence and analysis of human chromosome 8. |journal=Nature |volume=439 |issue= 7074 |pages= 331–5 |year= 2006 |pmid= 16421571 |doi= 10.1038/nature04406
*cite journal | author=Kraus DM, Elliott GS, Chute H, "et al." |title=CSMD1 is a novel multiple domain complement-regulatory protein highly expressed in the central nervous system and epithelial tissues. |journal=J. Immunol. |volume=176 |issue= 7 |pages= 4419–30 |year= 2006 |pmid= 16547280 |doi=

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