LASP1

LIM and SH3 protein 1, also known as LASP1, is a human gene.cite web | title = Entrez Gene: LASP1 LIM and SH3 protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3927| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization.cite web | title = Entrez Gene: LASP1 LIM and SH3 protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3927| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Tomasetto C, Régnier C, Moog-Lutz C, "et al." |title=Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. |journal=Genomics |volume=28 |issue= 3 |pages= 367–76 |year= 1996 |pmid= 7490069 |doi= 10.1006/geno.1995.1163
*cite journal | author=Tomasetto C, Moog-Lutz C, Régnier CH, "et al." |title=Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains. |journal=FEBS Lett. |volume=373 |issue= 3 |pages= 245–9 |year= 1995 |pmid= 7589475 |doi=
*cite journal | author=Chew CS, Parente JA, Zhou C, "et al." |title=Lasp-1 is a regulated phosphoprotein within the cAMP signaling pathway in the gastric parietal cell. |journal=Am. J. Physiol. |volume=275 |issue= 1 Pt 1 |pages= C56–67 |year= 1998 |pmid= 9688835 |doi=
*cite journal | author=Schreiber V, Moog-Lutz C, Régnier CH, "et al." |title=Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions. |journal=Mol. Med. |volume=4 |issue= 10 |pages= 675–87 |year= 1999 |pmid= 9848085 |doi=
*cite journal | author=Chew CS, Chen X, Parente JA, "et al." |title=Lasp-1 binds to non-muscle F-actin in vitro and is localized within multiple sites of dynamic actin assembly in vivo. |journal=J. Cell. Sci. |volume=115 |issue= Pt 24 |pages= 4787–99 |year= 2003 |pmid= 12432067 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Butt E, Gambaryan S, Göttfert N, "et al." |title=Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146. |journal=J. Biol. Chem. |volume=278 |issue= 18 |pages= 15601–7 |year= 2003 |pmid= 12571245 |doi= 10.1074/jbc.M209009200
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Li B, Zhuang L, Trueb B |title=Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1. |journal=J. Biol. Chem. |volume=279 |issue= 19 |pages= 20401–10 |year= 2004 |pmid= 15004028 |doi= 10.1074/jbc.M310304200
*cite journal | author=Keicher C, Gambaryan S, Schulze E, "et al." |title=Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase. |journal=Biochem. Biophys. Res. Commun. |volume=324 |issue= 1 |pages= 308–16 |year= 2004 |pmid= 15465019 |doi= 10.1016/j.bbrc.2004.08.235
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Tao WA, Wollscheid B, O'Brien R, "et al." |title=Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. |journal=Nat. Methods |volume=2 |issue= 8 |pages= 591–8 |year= 2005 |pmid= 16094384 |doi= 10.1038/nmeth776
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Grunewald TG, Kammerer U, Schulze E, "et al." |title=Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells. |journal=Exp. Cell Res. |volume=312 |issue= 7 |pages= 974–82 |year= 2006 |pmid= 16430883 |doi= 10.1016/j.yexcr.2005.12.016

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