GCM1

Glial cells missing homolog 1 (Drosophila), also known as GCM1, is a human gene.cite web | title = Entrez Gene: GCM1 glial cells missing homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8521| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.cite web | title = Entrez Gene: GCM1 glial cells missing homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8521| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Akiyama Y, Hosoya T, Poole AM, Hotta Y |title=The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 25 |pages= 14912–6 |year= 1997 |pmid= 8962155 |doi=
*cite journal | author=Yamada K, Ogawa H, Honda S, "et al." |title=A GCM motif protein is involved in placenta-specific expression of human aromatase gene. |journal=J. Biol. Chem. |volume=274 |issue= 45 |pages= 32279–86 |year= 1999 |pmid= 10542267 |doi=
*cite journal | author=Nait-Oumesmar B, Copperman AB, Lazzarini RA |title=Placental expression and chromosomal localization of the human Gcm 1 gene. |journal=J. Histochem. Cytochem. |volume=48 |issue= 7 |pages= 915–22 |year= 2000 |pmid= 10858268 |doi=
*cite journal | author=Yamada K, Ogawa H, Tamiya G, "et al." |title=Genomic organization, chromosomal localization, and the complete 22 kb DNA sequence of the human GCMa/GCM1, a placenta-specific transcription factor gene. |journal=Biochem. Biophys. Res. Commun. |volume=278 |issue= 1 |pages= 134–9 |year= 2001 |pmid= 11071865 |doi= 10.1006/bbrc.2000.3775
*cite journal | author=Yu C, Shen K, Lin M, "et al." |title=GCMa regulates the syncytin-mediated trophoblastic fusion. |journal=J. Biol. Chem. |volume=277 |issue= 51 |pages= 50062–8 |year= 2003 |pmid= 12397062 |doi= 10.1074/jbc.M209316200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Chen CP, Chen CY, Yang YC, "et al." |title=Decreased placental GCM1 (glial cells missing) gene expression in pre-eclampsia. |journal=Placenta |volume=25 |issue= 5 |pages= 413–21 |year= 2005 |pmid= 15081636 |doi= 10.1016/j.placenta.2003.10.014
*cite journal | author=Baczyk D, Satkunaratnam A, Nait-Oumesmar B, "et al." |title=Complex patterns of GCM1 mRNA and protein in villous and extravillous trophoblast cells of the human placenta. |journal=Placenta |volume=25 |issue= 6 |pages= 553–9 |year= 2004 |pmid= 15135239 |doi= 10.1016/j.placenta.2003.12.004
*cite journal | author=Schubert SW, Kardash E, Khan MA, "et al." |title=Interaction, cooperative promoter modulation, and renal colocalization of GCMa and Pitx2. |journal=J. Biol. Chem. |volume=279 |issue= 48 |pages= 50358–65 |year= 2005 |pmid= 15385555 |doi= 10.1074/jbc.M404587200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Yang CS, Yu C, Chuang HC, "et al." |title=FBW2 targets GCMa to the ubiquitin-proteasome degradation system. |journal=J. Biol. Chem. |volume=280 |issue= 11 |pages= 10083–90 |year= 2005 |pmid= 15640526 |doi= 10.1074/jbc.M413986200
*cite journal | author=Knerr I, Schubert SW, Wich C, "et al." |title=Stimulation of GCMa and syncytin via cAMP mediated PKA signaling in human trophoblastic cells under normoxic and hypoxic conditions. |journal=FEBS Lett. |volume=579 |issue= 18 |pages= 3991–8 |year= 2005 |pmid= 16004993 |doi= 10.1016/j.febslet.2005.06.029
*cite journal | author=Chang CW, Chuang HC, Yu C, "et al." |title=Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa. |journal=Mol. Cell. Biol. |volume=25 |issue= 19 |pages= 8401–14 |year= 2005 |pmid= 16166624 |doi= 10.1128/MCB.25.19.8401-8414.2005
*cite journal | author=Chuang HC, Chang CW, Chang GD, "et al." |title=Histone deacetylase 3 binds to and regulates the GCMa transcription factor. |journal=Nucleic Acids Res. |volume=34 |issue= 5 |pages= 1459–69 |year= 2006 |pmid= 16528103 |doi= 10.1093/nar/gkl048
*cite journal | author=Fujito N, Samura O, Miharu N, "et al." |title=Increased plasma mRNAs of placenta-specific 1 (PLAC1) and glial cells-missing 1 (GCM1) in mothers with pre-eclampsia. |journal=Hiroshima J. Med. Sci. |volume=55 |issue= 1 |pages= 9–15 |year= 2007 |pmid= 16594548 |doi=
*cite journal | author=Chou CC, Chang C, Liu JH, "et al." |title=Small ubiquitin-like modifier modification regulates the DNA binding activity of glial cell missing Drosophila homolog a. |journal=J. Biol. Chem. |volume=282 |issue= 37 |pages= 27239–49 |year= 2007 |pmid= 17646165 |doi= 10.1074/jbc.M700351200

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