SSR1

Signal sequence receptor, alpha (translocon-associated protein alpha), also known as SSR1, is a human gene.cite web | title = Entrez Gene: SSR1 signal sequence receptor, alpha (translocon-associated protein alpha)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6745| accessdate = ]

PBB_Summary
section_title =
summary_text = The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.cite web | title = Entrez Gene: SSR1 signal sequence receptor, alpha (translocon-associated protein alpha)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6745| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wei ML, Cresswell P |title=HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides. |journal=Nature |volume=356 |issue= 6368 |pages= 443–6 |year= 1992 |pmid= 1557127 |doi= 10.1038/356443a0
*cite journal | author=Vogel F, Hartmann E, Görlich D, Rapoport TA |title=Segregation of the signal sequence receptor protein in the rough endoplasmic reticulum membrane. |journal=Eur. J. Cell Biol. |volume=53 |issue= 2 |pages= 197–202 |year= 1991 |pmid= 1964414 |doi=
*cite journal | author=Hartmann E, Görlich D, Kostka S, "et al." |title=A tetrameric complex of membrane proteins in the endoplasmic reticulum. |journal=Eur. J. Biochem. |volume=214 |issue= 2 |pages= 375–81 |year= 1993 |pmid= 7916687 |doi=
*cite journal | author=Hartmann E, Prehn S |title=The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges. |journal=FEBS Lett. |volume=349 |issue= 3 |pages= 324–6 |year= 1994 |pmid= 8050590 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hu T, Guan T, Gerace L |title=Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. |journal=J. Cell Biol. |volume=134 |issue= 3 |pages= 589–601 |year= 1996 |pmid= 8707840 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Hirama T, Miller CW, Koeffler HP |title=Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation. |journal=FEBS Lett. |volume=455 |issue= 3 |pages= 223–7 |year= 1999 |pmid= 10437777 |doi=
*cite journal | author=Wang L, Dobberstein B |title=Oligomeric complexes involved in translocation of proteins across the membrane of the endoplasmic reticulum. |journal=FEBS Lett. |volume=457 |issue= 3 |pages= 316–22 |year= 1999 |pmid= 10471800 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhang H, Li XJ, Martin DB, Aebersold R |title=Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. |journal=Nat. Biotechnol. |volume=21 |issue= 6 |pages= 660–6 |year= 2003 |pmid= 12754519 |doi= 10.1038/nbt827
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Otsuki T, Ota T, Nishikawa T, "et al." |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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