TACC1

Transforming, acidic coiled-coil containing protein 1, also known as TACC1, is a human gene.cite web | title = Entrez Gene: TACC1 transforming, acidic coiled-coil containing protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6867| accessdate = ]

PBB_Summary
section_title =
summary_text = The function of this gene has not yet been determined; however, it is speculated that it may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers.cite web | title = Entrez Gene: TACC1 transforming, acidic coiled-coil containing protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6867| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lappin TR, Mullan RN, Stewart JP, "et al." |title=AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains. |journal=Leuk. Lymphoma |volume=43 |issue= 7 |pages= 1455–9 |year= 2003 |pmid= 12389629 |doi=
*cite journal | author=Still IH, Vince P, Cowell JK |title=The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines. |journal=Genomics |volume=58 |issue= 2 |pages= 165–70 |year= 1999 |pmid= 10366448 |doi= 10.1006/geno.1999.5829
*cite journal | author=Still IH, Hamilton M, Vince P, "et al." |title=Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon. |journal=Oncogene |volume=18 |issue= 27 |pages= 4032–8 |year= 1999 |pmid= 10435627 |doi= 10.1038/sj.onc.1202801
*cite journal | author=Kikuno R, Nagase T, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=
*cite journal | author=Gergely F, Karlsson C, Still I, "et al." |title=The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 26 |pages= 14352–7 |year= 2001 |pmid= 11121038 |doi= 10.1073/pnas.97.26.14352
*cite journal | author=Lauffart B, Howell SJ, Tasch JE, "et al." |title=Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells. |journal=Biochem. J. |volume=363 |issue= Pt 1 |pages= 195–200 |year= 2002 |pmid= 11903063 |doi=
*cite journal | author=Linē A, Stengrēvics A, Slucka Z, "et al." |title=Serological identification and expression analysis of gastric cancer-associated genes. |journal=Br. J. Cancer |volume=86 |issue= 11 |pages= 1824–30 |year= 2002 |pmid= 12087473 |doi= 10.1038/sj.bjc.6600321
*cite journal | author=Conte N, Charafe-Jauffret E, Delaval B, "et al." |title=Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators. |journal=Oncogene |volume=21 |issue= 36 |pages= 5619–30 |year= 2002 |pmid= 12165861 |doi= 10.1038/sj.onc.1205658
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Line A, Slucka Z, Stengrevics A, "et al." |title=Altered splicing pattern of TACC1 mRNA in gastric cancer. |journal=Cancer Genet. Cytogenet. |volume=139 |issue= 1 |pages= 78–83 |year= 2003 |pmid= 12547166 |doi=
*cite journal | author=Conte N, Delaval B, Ginestier C, "et al." |title=TACC1-chTOG-Aurora A protein complex in breast cancer. |journal=Oncogene |volume=22 |issue= 50 |pages= 8102–16 |year= 2003 |pmid= 14603251 |doi= 10.1038/sj.onc.1206972
*cite journal | author=Gangisetty O, Lauffart B, Sondarva GV, "et al." |title=The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases. |journal=Oncogene |volume=23 |issue= 14 |pages= 2559–63 |year= 2004 |pmid= 14767476 |doi= 10.1038/sj.onc.1207424
*cite journal | author=Delaval B, Ferrand A, Conte N, "et al." |title=Aurora B -TACC1 protein complex in cytokinesis. |journal=Oncogene |volume=23 |issue= 26 |pages= 4516–22 |year= 2004 |pmid= 15064709 |doi= 10.1038/sj.onc.1207593
*cite journal | author=Still IH, Vettaikkorumakankauv AK, DiMatteo A, Liang P |title=Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms. |journal=BMC Evol. Biol. |volume=4 |issue= |pages= 16 |year= 2004 |pmid= 15207008 |doi= 10.1186/1471-2148-4-16
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Lauffart B, Dimatteo A, Vaughan MM, "et al." |title=Temporal and spatial expression of TACC1 in the mouse and human. |journal=Dev. Dyn. |volume=235 |issue= 6 |pages= 1638–47 |year= 2007 |pmid= 16496324 |doi= 10.1002/dvdy.20724
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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