GNAT2

Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2, also known as GNAT2, is a human gene.cite web | title = Entrez Gene: GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2780| accessdate = ]

PBB_Summary
section_title =
summary_text = Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.cite web | title = Entrez Gene: GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2780| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wilkie TM, Gilbert DJ, Olsen AS, "et al." |title=Evolution of the mammalian G protein alpha subunit multigene family. |journal=Nat. Genet. |volume=1 |issue= 2 |pages= 85–91 |year= 1993 |pmid= 1302014 |doi= 10.1038/ng0592-85
*cite journal | author=Arshavsky VYu , Gray-Keller MP, Bownds MD |title=cGMP suppresses GTPase activity of a portion of transducin equimolar to phosphodiesterase in frog rod outer segments. Light-induced cGMP decreases as a putative feedback mechanism of the photoresponse. |journal=J. Biol. Chem. |volume=266 |issue= 28 |pages= 18530–7 |year= 1991 |pmid= 1655754 |doi=
*cite journal | author=Mazzoni MR, Malinski JA, Hamm HE |title=Structural analysis of rod GTP-binding protein, Gt. Limited proteolytic digestion pattern of Gt with four proteases defines monoclonal antibody epitope. |journal=J. Biol. Chem. |volume=266 |issue= 21 |pages= 14072–81 |year= 1991 |pmid= 1713215 |doi=
*cite journal | author=Fawzi AB, Fay DS, Murphy EA, "et al." |title=Rhodopsin and the retinal G-protein distinguish among G-protein beta gamma subunit forms. |journal=J. Biol. Chem. |volume=266 |issue= 19 |pages= 12194–200 |year= 1991 |pmid= 1905716 |doi=
*cite journal | author=Kubo M, Hirano T, Kakinuma M |title=Molecular cloning and sequence analysis of cDNA and genomic DNA for the human cone transducin alpha subunit. |journal=FEBS Lett. |volume=291 |issue= 2 |pages= 245–8 |year= 1991 |pmid= 1936270 |doi=
*cite journal | author=Lerea CL, Bunt-Milam AH, Hurley JB |title=Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina. |journal=Neuron |volume=3 |issue= 3 |pages= 367–76 |year= 1990 |pmid= 2534964 |doi=
*cite journal | author=Blatt C, Eversole-Cire P, Cohn VH, "et al." |title=Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 20 |pages= 7642–6 |year= 1988 |pmid= 2902634 |doi=
*cite journal | author=Buss JE, Mumby SM, Casey PJ, "et al." |title=Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 21 |pages= 7493–7 |year= 1987 |pmid= 3118369 |doi=
*cite journal | author=Hirano T |title= [Analysis of cell specific transcription of the human cone transducin alpha subunit gene] |journal=Hokkaido Igaku Zasshi |volume=68 |issue= 6 |pages= 885–93 |year= 1994 |pmid= 8112713 |doi=
*cite journal | author=Morris TA, Fong SL |title=Characterization of the gene encoding human cone transducin alpha-subunit (GNAT2). |journal=Genomics |volume=17 |issue= 2 |pages= 442–8 |year= 1993 |pmid= 8406495 |doi= 10.1006/geno.1993.1345
*cite journal | author=Morris TA, Fong WB, Ward MJ, "et al." |title=Localization of upstream silencer elements involved in the expression of cone transducin alpha-subunit (GNAT2). |journal=Invest. Ophthalmol. Vis. Sci. |volume=38 |issue= 1 |pages= 196–206 |year= 1997 |pmid= 9008644 |doi=
*cite journal | author=Kohl S, Baumann B, Rosenberg T, "et al." |title=Mutations in the cone photoreceptor G-protein alpha-subunit gene GNAT2 in patients with achromatopsia. |journal=Am. J. Hum. Genet. |volume=71 |issue= 2 |pages= 422–5 |year= 2002 |pmid= 12077706 |doi=
*cite journal | author=Aligianis IA, Forshew T, Johnson S, "et al." |title=Mapping of a novel locus for achromatopsia (ACHM4) to 1p and identification of a germline mutation in the alpha subunit of cone transducin (GNAT2). |journal=J. Med. Genet. |volume=39 |issue= 9 |pages= 656–60 |year= 2002 |pmid= 12205108 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Piña AL, Baumert U, Loyer M, Koenekoop RK |title=A three base pair deletion encoding the amino acid (lysine-270) in the alpha-cone transducin gene. |journal=Mol. Vis. |volume=10 |issue= |pages= 265–71 |year= 2004 |pmid= 15094710 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rosenberg T, Baumann B, Kohl S, "et al." |title=Variant phenotypes of incomplete achromatopsia in two cousins with GNAT2 gene mutations. |journal=Invest. Ophthalmol. Vis. Sci. |volume=45 |issue= 12 |pages= 4256–62 |year= 2005 |pmid= 15557429 |doi= 10.1167/iovs.04-0317

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