Nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs), also known as NOLA1, is a human gene.cite web | title = Entrez Gene: NOLA1 nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)| url =| accessdate = ]

section_title =
summary_text = This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.cite web | title = Entrez Gene: NOLA1 nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)| url =| accessdate = ]


Further reading

citations =
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*cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, "et al." |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=
*cite journal | author=Ardell MD, Aragon I, Oliveira L, "et al." |title=The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit. |journal=FEBS Lett. |volume=389 |issue= 2 |pages= 213–8 |year= 1996 |pmid= 8766832 |doi=
*cite journal | author=Dragon F, Pogacić V, Filipowicz W |title=In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs. |journal=Mol. Cell. Biol. |volume=20 |issue= 9 |pages= 3037–48 |year= 2000 |pmid= 10757788 |doi=
*cite journal | author=Pogacić V, Dragon F, Filipowicz W |title=Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. |journal=Mol. Cell. Biol. |volume=20 |issue= 23 |pages= 9028–40 |year= 2000 |pmid= 11074001 |doi=
*cite journal | author=Pellizzoni L, Baccon J, Charroux B, Dreyfuss G |title=The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1. |journal=Curr. Biol. |volume=11 |issue= 14 |pages= 1079–88 |year= 2001 |pmid= 11509230 |doi=
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Whitehead SE, Jones KW, Zhang X, "et al." |title=Determinants of the interaction of the spinal muscular atrophy disease protein SMN with the dimethylarginine-modified box H/ACA small nucleolar ribonucleoprotein GAR1. |journal=J. Biol. Chem. |volume=277 |issue= 50 |pages= 48087–93 |year= 2003 |pmid= 12244096 |doi= 10.1074/jbc.M204551200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wang C, Meier UT |title=Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins. |journal=EMBO J. |volume=23 |issue= 8 |pages= 1857–67 |year= 2005 |pmid= 15044956 |doi= 10.1038/sj.emboj.7600181
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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